Nwaejike Nnamdi, Elbur Ehab, Rammohan Kandadai S, Shah Rajesh
Department of Cardiothoracic Surgery, University Hospitals of South Manchester, Wythenshawe, UK.
Interact Cardiovasc Thorac Surg. 2013 Dec;17(6):988-90. doi: 10.1093/icvts/ivt396. Epub 2013 Aug 30.
A 29-year old woman at 26 weeks gestation (gravida 3 and para 0) presented with an acute left-sided pneumothorax. She had a 10 pack-year smoking history and no other relevant medical history. Over the next 3 weeks, she had three recurrences of her left-sided pneumothorax, each of which was managed by intercostal drain insertion. During the fourth episode of pneumothorax, after chest drain insertion there was a continued air-leak for 4 days. She was referred to the cardiothoracic service for further management of this problem. A best evidence topic was constructed according to a structured protocol to answer the question: in pregnant patients with a recurrent or persistent pneumothorax, is surgery safer compared with conservative treatment for the wellbeing of the patient and the foetus? The 2010 guidelines for the management of pneumothorax state that there is Level C evidence that simple observation and aspiration are usually effective during pregnancy, with elective assisted delivery and regional anaesthesia at or near term. The guidelines also state Level D evidence that a video-assisted thoracoscopic surgery (VATS) procedure should be considered after birth. Three hundred and eighty-four papers were found, and from these, four papers were identified describing 79 cases of pneumothorax in pregnancy to provide the best evidence to answer the question. Conservative treatment by observation alone with or without tube thoracostomy compared with surgical treatment by VATS or thoracotomy are the options used in the observed literature reviews. All reports observe no difference in outcome to the mother or foetus if a conservative approach (observation or tube thoracostomy) is used compared with surgery prior to the delivery of the baby. However, an initial conservative approach could lead to surgery after delivery for a persistent pneumothorax in as much as 40% of patients. A persistent pneumothorax after delivery that might require surgery delays discharge home and compromises the normal interaction between the mother and new-born child, which might be distressing. For informed consent, the implications of the risk of persistent pneumothorax requiring surgery after delivery where a conservative approach is used initially should be discussed with the patient and family to aid decision making.
一名孕26周的29岁女性(孕3产0)因急性左侧气胸入院。她有10年的吸烟史,无其他相关病史。在接下来的3周内,她左侧气胸复发3次,每次均通过肋间置管引流进行处理。在第四次气胸发作时,胸腔引流管置入后持续漏气4天。她被转诊至心胸外科以进一步处理该问题。根据结构化方案构建了一个最佳证据主题,以回答以下问题:对于复发性或持续性气胸的孕妇,就患者和胎儿的健康而言,手术治疗与保守治疗相比是否更安全?2010年气胸管理指南指出,有C级证据表明,孕期单纯观察和抽气通常有效,可在足月或接近足月时选择辅助分娩和区域麻醉。该指南还指出有D级证据表明,产后应考虑行电视辅助胸腔镜手术(VATS)。共检索到384篇论文,从中筛选出4篇描述79例孕期气胸病例的论文,以提供回答该问题的最佳证据。观察性文献综述中使用的选项包括单纯观察(无论是否行胸腔闭式引流)的保守治疗与VATS或开胸手术的手术治疗。所有报告均观察到,与分娩前手术相比,采用保守方法(观察或胸腔闭式引流)对母亲或胎儿的结局无差异。然而,初始采用保守方法可能导致40%的患者产后因持续性气胸而需要手术。产后持续性气胸可能需要手术,这会延迟出院,并影响母亲与新生儿之间的正常互动,可能令人苦恼。为了获得知情同意,应与患者及其家属讨论初始采用保守方法后产后需要手术治疗持续性气胸的风险,以帮助做出决策。