Gandhi Sachin, Kulkarni Santosh, Mishra Prasun, Thekedar Pallavi
Department of Laryngology, Deenanath Mangeshkar Hospital, Pune, Maharashtra India.
Indian J Otolaryngol Head Neck Surg. 2012 Sep;64(3):244-7. doi: 10.1007/s12070-011-0333-4. Epub 2011 Dec 3.
Tuberculosis is the most frequent granulomatous disease involving larynx. In most cases it is secondary to pulmonary tuberculosis. Incidence of tuberculosis is now on a rise due to increase in incidence of immune deficiency states. Here we present a report of clinical characteristic of laryngeal tuberculosis based on our experience of 10 cases. A detailed retrospective analysis of 10 patients of laryngeal tuberculosis was done at our tertiary care laryngology centre. Majority of patients had change of voice and dry cough. All the patients had hyperemia and edema of vocal cords. 80% patients had involvement of the arytenoids and ary-epiglottic folds. Frank granulomatous growth was seen in 70% of patients. In all patients histopathological report was consistent with tubercular granuloma. Two patients had associated pulmonary tuberculosis. Eight patients did not reveal any feature suggestive of previous or co-existent pulmonary tuberculosis. All patients responded to chemotherapy with complete resolution. Primary laryngeal tuberculosis is not as rare as generally considered. This series provides an insight towards clinical feature, growth pattern and management of tuberculosis of larynx.
结核病是最常见的累及喉部的肉芽肿性疾病。在大多数情况下，它继发于肺结核。由于免疫缺陷状态发病率的增加，结核病的发病率目前呈上升趋势。在此，我们根据10例病例的经验，报告喉结核的临床特征。在我们的三级护理喉科学中心，对10例喉结核患者进行了详细的回顾性分析。大多数患者有声音改变和干咳。所有患者均有声带充血和水肿。80%的患者杓状软骨和杓会厌襞受累。70%的患者可见明显的肉芽肿生长。所有患者的组织病理学报告均符合结核性肉芽肿。2例患者合并肺结核。8例患者未发现任何提示既往或并存肺结核的特征。所有患者对化疗有反应，症状完全缓解。原发性喉结核并不像一般认为的那样罕见。本系列研究为喉结核的临床特征、生长模式及治疗提供了见解。
