Department of Otorhinolaryngology, IMS and SUM Hospital, Siksha "O" Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.
Department of Community Medicine, IMS and SUM Hospital, Siksha "O" Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.
J Voice. 2019 Sep;33(5):812.e9-812.e14. doi: 10.1016/j.jvoice.2018.04.010.
Primary laryngeal tuberculosis is a chronic bacterial infection of the larynx by Mycobacterium tuberculosis without affecting the lungs. It is a rare type of extrapulmonary tuberculosis seen in clinical practice.
This study aimed to evaluate the clinical presentation, diagnosis, and treatment of primary laryngeal tuberculosis at a tertiary care teaching hospital in eastern India.
This is a retrospective study of 11 cases of primary laryngeal tuberculosis managed between December 2013 and January 2018. The detailed clinical presentations, investigations, and treatment of primary laryngeal tuberculosis of the patients were studied.
Primary laryngeal tuberculosis is common in men with mean age of 38.63 years. Hoarseness of the voice is the most common symptom, and the most common site for primary laryngeal tuberculosis is the vocal fold with ulcerative lesion. Endoscopic examinations of the larynx in laryngeal tuberculosis are nonspecific and are to be confused with laryngeal cancer. Histopathological and bacteriological examinations are confirmatory tests for the diagnosis. After confirmation of the diagnosis, all patients had taken antitubercular therapy for 6 months, which gave excellent outcome.
Delayed diagnosis or untreatable laryngeal tuberculosis will lead to high morbidity and mortality of the patient. Although primary laryngeal tuberculosis has nonspecific clinical presentations, it is very important to have a high index of suspiciousness to rule out tubercular lesion in the larynx as this disease is curable.
原发性喉结核是一种由结核分枝杆菌引起的喉部慢性细菌性感染，不影响肺部。它是临床实践中罕见的肺外结核类型。
本研究旨在评估印度东部一家三级护理教学医院原发性喉结核的临床表现、诊断和治疗。
这是一项对 2013 年 12 月至 2018 年 1 月期间收治的 11 例原发性喉结核患者进行的回顾性研究。研究了患者的详细临床表现、检查和原发性喉结核的治疗。
原发性喉结核多见于男性，平均年龄为 38.63 岁。声音嘶哑是最常见的症状，原发性喉结核最常见的部位是声带伴溃疡性病变。喉结核的喉镜检查是非特异性的，容易与喉癌混淆。组织病理学和细菌学检查是诊断的确诊试验。确诊后，所有患者均接受了 6 个月的抗结核治疗，效果极佳。
诊断延迟或治疗无效的喉结核会导致患者高发病率和死亡率。虽然原发性喉结核的临床表现不具特异性，但高度怀疑喉部结核病变非常重要，因为这种疾病是可治愈的。
