Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA.
Allergy Asthma Proc. 2013 Sep-Oct;34(5):427-33. doi: 10.2500/aap.2013.34.3687.
Asthma is associated with significant morbidity and mortality in the geriatric population. Despite the rising incidence of asthma in people >65 years of age, the diagnosis is frequently missed in this population. Factors that contribute to this include respiratory changes caused by aging, immunosenescence, lack of symptoms, polypharmacy, clinician unawareness, and lack of evidence-based guidelines for diagnosis and management that target this population. This literature review addresses the current state of research in this area. Age-related changes influence the pathophysiology and role of allergy in elderly asthmatic patients. Specific obstacles encountered in caring for these patients are discussed. Asthma in the elderly and younger population are compared. We conclude with a broad set of goals to guide future management driven by a multidiscipline approach.
哮喘与老年人群的发病率和死亡率显著相关。尽管 >65 岁人群的哮喘发病率不断上升，但在该人群中，哮喘的诊断常常被忽视。导致这种情况的因素包括衰老引起的呼吸变化、免疫衰老、缺乏症状、多药治疗、临床医生意识不足以及缺乏针对该人群的基于证据的诊断和管理指南。本文献综述讨论了该领域的研究现状。与年龄相关的变化影响老年哮喘患者的病理生理学和过敏作用。讨论了在照顾这些患者时遇到的具体障碍。比较了老年和年轻人群中的哮喘。我们最后提出了一套广泛的目标，以多学科方法为指导，指导未来的管理。
