The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel; Judea Regional Research and Development Center, Carmel 90404, Israel.
Trends Genet. 2013 Oct;29(10):559-60. doi: 10.1016/j.tig.2013.08.003. Epub 2013 Aug 30.
Understanding the genetic basis of human longevity remains a challenge but could lead to life-extending interventions and better treatments for age-related diseases. Toward this end we developed the LongevityMap (http://genomics.senescence.info/longevity/), the first database of genes, loci, and variants studied in the context of human longevity and healthy ageing. We describe here its content and interface, and discuss how it can help to unravel the genetics of human longevity.
理解人类长寿的遗传基础仍然是一个挑战，但它可能会带来延长寿命的干预措施和针对与年龄相关的疾病的更好治疗方法。为此，我们开发了 LongevityMap（http://genomics.senescence.info/longevity/），这是第一个在人类长寿和健康衰老背景下研究的基因、基因座和变异体数据库。我们在这里描述了它的内容和界面，并讨论了它如何帮助揭示人类长寿的遗传学。
