[伴有眼肌麻痹的共济失调：抗 GQ1b 抗体阳性的米勒-费希尔综合征]

[Ataxia with ophthalmoplegia: Miller-Fisher syndrome with anti-GQ1b antibody positivity].

作者信息

Guilloton L, Camarasa C, Agard E, Tondeur G, Dot C, Drouet A

机构信息

Service de neurologie, HIA Desgenettes, 108, boulevard Pinel, 69275 Lyon cedex 03, France.

出版信息

J Fr Ophtalmol. 2014 Feb;37(2):89-92. doi: 10.1016/j.jfo.2013.05.026. Epub 2014 Feb 7.

DOI:10.1016/j.jfo.2013.05.026

PMID:24513384

Abstract

Miller-Fisher syndrome is defined as ophthalmoplegia, ataxia and areflexia. Considered as a variant of Guillain-Barré syndrome, it differs in its clinical presentation and by anti-GQ1b antibody positivity. The authors report a case of Miller-Fisher syndrome characterized by ataxia and complete ophthalmoplegia. Through this example, the range of ophthalmologic clinical manifestations are discussed.

摘要

米勒-费希尔综合征的定义为眼肌麻痹、共济失调和无反射。作为吉兰-巴雷综合征的一种变体，它在临床表现和抗GQ1b抗体阳性方面有所不同。作者报告了一例以共济失调和完全性眼肌麻痹为特征的米勒-费希尔综合征病例。通过这个例子，讨论了眼科临床表现的范围。