Karayan J, Lacoste L, Breuil K
Département d'Anesthésiologie, Hôpital Jean-Bernard, Poitiers.
Ann Fr Anesth Reanim. 1990;9(4):396-7. doi: 10.1016/S0750-7658(05)80256-4.
A case is reported of allergy to ketamine substantiated 2 years after the accident. The female patient had ketamine for the removal of a mole. During this procedure, she developed a generalized rash and laryngospasm; the use of adrenaline was required. Since that time, although no confirmatory investigations had been carried out, she had been given a paper identifying Ketalar as being the involved drug. Investigations were carried out after she had been given a further anaesthetic (without using ketamine) 2 years after the accident. These confirmed an allergic reaction to ketamine, and not to the solvent, chlorobutanol.