Division of Genetics and.
Annu Rev Genomics Hum Genet. 2013;14:491-513. doi: 10.1146/annurev-genom-092010-110722.
Communicating genetic risk information in ways that maximize understanding and promote health is increasingly important given the rapidly expanding availability and capabilities of genomic technologies. A well-developed literature on risk communication in general provides guidance for best practices, including presentation of information in multiple formats, attention to framing effects, use of graphics, sensitivity to the way numbers are presented, parsimony of information, attentiveness to emotions, and interactivity as part of the communication process. Challenges to communicating genetic risk information include deciding how best to tailor it, streamlining the process, deciding what information to disclose, accepting that communications may have limited influence, and understanding the impact of context. Meeting these challenges has great potential for empowering individuals to adopt healthier lifestyles and improve public health, but will require multidisciplinary approaches and collaboration.
鉴于基因组技术的快速发展和应用,以最大化理解和促进健康为目标来传递遗传风险信息变得越来越重要。一般来说,关于风险沟通的完善文献为最佳实践提供了指导,包括以多种格式呈现信息、关注框架效应、使用图形、注意数字的呈现方式、信息的简洁性、关注情感以及将交互性作为沟通过程的一部分。遗传风险信息沟通面临的挑战包括决定如何最好地调整信息、简化流程、决定披露哪些信息、接受沟通可能影响力有限以及理解背景的影响。应对这些挑战有很大的潜力使个人能够采取更健康的生活方式并改善公共卫生,但这将需要多学科方法和协作。