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Researches on antiinflammatory agents. Studies on some new 3-(pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-ones and -quinazolin-4(3H)-ones.

作者信息

Daidone G, Plescia S, Raffa D, Bajardi M L, Matera M, Caruso A, Leone M G

机构信息

Dipartimento di Chimica e Technologie Farmaceutiche, Università di Palermo.

出版信息

Farmaco. 1990 Apr;45(4):391-8.

PMID:2400513
Abstract

Following our research on analgesic and antiinflammatory active compounds containing the pyrazole nucleus, a number of 3-(pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-ones and quinazolin-4(3H)-ones was synthetized and tested. The results of tests for analgesic, antiexudative and antioedema activities, as well as for induction of lesion in the gastric mucosa, are reported and discussed.

摘要

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