Type I and IV collagen and fibrinogen binding to Aeromonas species isolated from various infections.

Collagen binding is a common property of strains of Aeromonas species. However, agglutination of latex beads coated with types I and IV collagen and fibrinogen with Aeromonas cells varied among strains of Aeromonas species and their source of isolation. Culture media and growth conditions greatly influenced expression of Aeromonas cell surface receptors to bind collagen (types I and IV) and fibrinogen immobilized on the latex particles as suggested by the particle agglutination assay (PAA). Aeromonas cells aggregated with the differentially coated latex beads in a specified manner. Furthermore, the PAA method was found to be rapid, easy to perform and sensitive for routine screening of a large number of strains for serum and connective-tissue protein cell surface receptors.