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系统回顾和荟萃分析:屈肌腱腱鞘炎的工作相关病因——对其认定为职业病的批判性评价。

Systematic review and meta-analysis on the work-related cause of de Quervain tenosynovitis: a critical appraisal of its recognition as an occupational disease.

机构信息

Tübingen and Stuttgart, Germany From the Department of Plastic, Hand, and Reconstructive Surgery, Burn Center, BG-Trauma Center, and the Institute for Clinical Epidemiology and Applied Biometry, Eberhard-Karl University of Tübingen; and the Department for Plastic Surgery, Marienhospital Stuttgart.

出版信息

Plast Reconstr Surg. 2013 Dec;132(6):1479-1491. doi: 10.1097/01.prs.0000434409.32594.1b.

DOI:10.1097/01.prs.0000434409.32594.1b
PMID:24005369
Abstract

BACKGROUND

The authors systematically reviewed all of the etiopathologic factors discussed in the literature to verify the classification of de Quervain tenosynovitis on the list of occupational diseases.

METHODS

The authors searched Ovid MEDLINE, EMBASE, and the Cochrane Library for articles discussing the cause of de Quervain tenosynovitis. The literature was classified by the level of evidence presented, the etiopathologic hypothesis discussed, the authors' conclusion about the role of the etiopathologic hypothesis, and the first author's professional background. The quality of reporting of the observational studies was evaluated by an extended Strengthening the Reporting of Observational Studies in Epidemiology statement checklist. A meta-analysis of all controlled cohort studies was performed. The Bradford Hill criteria were used to evaluate a causal relationship between de Quervain tenosynovitis and occupational risk factors.

RESULTS

A total of 179 references were found, and 80 articles were included. On average, only 35 percent (median, 35 percent; range, 16 to 60 percent) of all items on the extended Strengthening the Reporting of Observational Studies in Epidemiology checklist were addressed per article. The meta-analysis to evaluate the strength of the association between de Quervain tenosynovitis and (1) repetitive, (2) forceful, or (3) ergonomically stressful manual work suggested an odds ratio of 2.89 (95 percent CI, 1.4 to 5.97; p = 0.004). No evidence was found to support the Bradford Hill criteria for a causal relationship between de Quervain tenosynovitis and occupational risk factors.

CONCLUSION

No sufficient scientific evidence was provided to confirm a causal relationship between de Quervain tenosynovitis and occupational risk factors.

CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III.

摘要

背景

作者系统地回顾了文献中讨论的所有病因学因素,以验证狭窄性腱鞘炎被列为职业病的分类。

方法

作者在 Ovid MEDLINE、EMBASE 和 Cochrane 图书馆中搜索了讨论狭窄性腱鞘炎病因的文章。根据提出的证据水平、讨论的病因假说、作者对病因假说作用的结论以及第一作者的专业背景对文献进行分类。使用扩展后的观察性研究流行病学报告规范检查表评估观察性研究的报告质量。对所有对照队列研究进行了荟萃分析。使用布拉德福希尔标准评估狭窄性腱鞘炎与职业危险因素之间的因果关系。

结果

共发现 179 篇参考文献,其中 80 篇文章被纳入。平均而言,每篇文章仅解决了扩展后的观察性研究流行病学报告规范检查表中所有项目的 35%(中位数,35%;范围,16%至 60%)。评估狭窄性腱鞘炎与(1)重复性、(2)用力或(3)符合人体工程学的应激性手工劳动之间关联强度的荟萃分析表明,比值比为 2.89(95%CI,1.4 至 5.97;p = 0.004)。没有证据支持狭窄性腱鞘炎与职业危险因素之间因果关系的布拉德福希尔标准。

结论

没有充分的科学证据证实狭窄性腱鞘炎与职业危险因素之间存在因果关系。

临床问题/证据水平:风险,III。

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