Patera Nikolaus, Wild Claudia
Ludwig Boltzmann Institut für Health Technology Assessment, Garnisongasse 7/20, 1090, Wien, Österreich,
Wien Med Wochenschr. 2013 Sep;163(17-18):409-19. doi: 10.1007/s10354-013-0232-2. Epub 2013 Sep 5.
Bowel cancer is frequent, early stages have much better prognosis and drug treatment of late stages is increasingly very expensive. Screening for colorectal cancer has the potential for both early detection and prevention. For a screening intervention colonoscopy is very invasive and holds the small risk of serious complications. Colonoscopy plays a key role for further diagnosis and intervention in all programs. Current international screening activities are presented. The emerging evidence on effectiveness of screening suggests that all strategies may have similar effect sizes. Participation rates and quality assurance thus are of key importance for realizing potential net health gains. Participation rates are higher for stool tests than for sigmoidoscopy and colonoscopy. For quality assurance of screening-colonoscopy an established range of quality measures is available. The possibility of systematic quality assurance also in the context of opportunistic screening like in Austria is proven by Germany and Poland.
肠癌很常见,早期预后要好得多,而晚期的药物治疗费用越来越高。结直肠癌筛查具有早期发现和预防的潜力。对于筛查干预,结肠镜检查具有很强的侵入性,且有发生严重并发症的小风险。结肠镜检查在所有项目的进一步诊断和干预中都起着关键作用。本文介绍了当前的国际筛查活动。关于筛查有效性的新证据表明,所有策略可能具有相似的效应量。因此,参与率和质量保证对于实现潜在的净健康收益至关重要。粪便检测的参与率高于乙状结肠镜检查和结肠镜检查。对于筛查结肠镜检查的质量保证,有一系列既定的质量措施。德国和波兰证明了在奥地利等机会性筛查背景下进行系统质量保证的可能性。