LEAD UMR CNRS 5022, University of Burgundy, France.
J Neuropsychol. 2013 Sep;7(2):164-78. doi: 10.1111/jnp.12014. Epub 2013 Mar 21.
This study examined the effects of providing cues to facilitate autobiographical memory retrieval in Parkinson's disease. Previous findings have shown that individuals with Parkinson's disease retrieve fewer specific autobiographical memories than older adult controls. These findings are clinically significant since the quality of autobiographical memory is linked to identity and sense of self. In the current study, 16 older adults with Parkinson's disease without dementia and 16 matched older adult controls were given 3 min in which to recall autobiographical memories associated with five different time periods and to give each memory a short title. Participants were later asked to retrieve the memories in three phases: firstly in a free recall phase; secondly in response to general cues (time periods) and finally in response to specific cues (the short titles previously given). The number of memories and the quality of the memory (general or specific) was recorded in each condition. Compared with matched older adult controls, the Parkinson's disease group was impaired in retrieving the memories that they had previously given in the free recall phase and in response to general cues. The performance of the group with Parkinson's disease was only equivalent to the older adults when they retrieved memories in response to self-generated cues. The findings are discussed in relation to theories of autobiographical memory and the neuropsychology of Parkinson's disease.
本研究考察了提供线索以促进帕金森病患者自传体记忆检索的效果。先前的研究发现，帕金森病患者比老年对照组检索到的特定自传体记忆更少。这些发现具有临床意义，因为自传体记忆的质量与身份和自我意识有关。在当前的研究中，16 名无痴呆的帕金森病老年患者和 16 名匹配的老年对照组被给予 3 分钟的时间来回忆与五个不同时间段相关的自传体记忆，并为每个记忆取一个简短的标题。随后，参与者被要求在三个阶段检索记忆：首先是在自由回忆阶段；其次是响应一般线索（时间段），最后是响应特定线索（之前给出的简短标题）。在每种情况下都记录了记忆的数量和记忆的质量（一般或特定）。与匹配的老年对照组相比，帕金森病组在自由回忆阶段和响应一般线索时检索先前给出的记忆方面存在障碍。当帕金森病组的患者在响应自我生成的线索时检索记忆时，他们的表现仅等同于老年组。研究结果结合自传体记忆理论和帕金森病的神经心理学进行了讨论。
