Leeds Memory Group, Institute of Psychological Sciences, University of Leeds, UK.
Cortex. 2010 Jun;46(6):787-93. doi: 10.1016/j.cortex.2009.08.006. Epub 2009 Aug 27.
Autobiographical memory (AM) concerns the ability to remember past events from one's own life and consists of autobiographical knowledge (personal facts) and autobiographical incidents (personal events). The novelty of this research was to assess both personal factual and personal event AM in Parkinson's disease (PD) for specified lifetime periods. An autobiographical fluency task was used in which participants were asked to recall personal events and personal facts from five separate lifetime periods. Previous findings as well the brain regions affected in PD lead to the hypothesis that Parkinson's patients would recall less autobiographical memories especially for the most recent lifetime periods. Sixteen non-demented and non-depressed Parkinson's patients and sixteen age-education-matched controls participated. The results showed a temporal gradient for the recall of personal events in Parkinson's patients as they recalled fewer events for recent time periods. The PD group also had more difficulties in recalling autobiographical events rather than an autobiographical knowledge. The difficulty in recalling autobiographical events was characterized by overgenerality, with PD patients failing to generate specific episodic memories.
自传体记忆（AM）涉及从个人生活中回忆过去事件的能力，包括自传体知识（个人事实）和自传体事件（个人事件）。本研究的新颖之处在于评估帕金森病（PD）患者在特定生命时期的个人事实和个人事件 AM。使用自传体流畅性任务，要求参与者从五个不同的生命时期回忆个人事件和个人事实。先前的研究结果以及 PD 患者受影响的大脑区域导致了这样的假设，即帕金森病患者会回忆起较少的自传体记忆，尤其是最近的生命时期。16 名非痴呆和非抑郁的帕金森病患者和 16 名年龄教育匹配的对照组参与了研究。结果表明，帕金森病患者的个人事件回忆存在时间梯度，因为他们回忆起最近时间段的事件较少。PD 组在回忆自传体事件方面也比回忆自传体知识更困难。回忆自传体事件的困难表现为过度概括，PD 患者无法产生特定的情节记忆。
