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[摩洛哥苏斯-马萨-德拉地区的中毒自杀情况]

[Suicide by poisoning in the Souss-Massa-Drâa region of Morocco].

作者信息

Mahir Siham, Soulaymani Abdelmajid, Hami Hind, Mokhtari Abdelrhani, Benali Doha, Ouammi Lahcen, Windy Maria, Benchekh Rachida Soulaymani

机构信息

Laboratoire de Génétique et Biométrie, Faculté des Sciences, Université Ibn Tofail, Kénitra, Maroc.

出版信息

Sante Publique. 2013 May-Jun;25(3):343-50.

Abstract

INTRODUCTION

Deliberate self-poisoning is a serious problem in Morocco, including in the Souss-Massa-Drâa region. However, our understanding of the problem of suicidal poisoning remains limited.

SUBJECT

This paper aims to describe the characteristics of patients, toxic substances and poisoning and to identify the risk factors influencing patient outcomes.

METHODS

A retrospective study was conducted of all cases of deliberate self-poisoning recorded between 1981 and 2007 by the Centre Anti-Poison et de Pharmacovigilance du Maroc.

RESULTS

1,130 cases of self-poisoning were identified. The mean age was 25 ± 10.1 years and the sex ratio was 0.4. Paraphenylenediamine was the most common cause of death (48 deaths), followed by hydrochloric acid (15 deaths). A close relationship was found between progression to healing and female adolescents and between progression to death and men in other age groups. The study also found that patients who used paraphenylenediamine were twelve times more likely to die (CI95%: 7.4%-19.2%) than those who used other substances. Patients with respiratory and cardiovascular conditions had a relative risk of 9.8 (CI95%: 6.3%-16%) and 3.6 (CI95%: 2.3%-5.7%). Of the 937 cases with known outcome, 89 died (9.5%).

摘要

引言

蓄意自我中毒在摩洛哥是一个严重问题,包括在苏斯-马萨-德拉地区。然而,我们对自杀性中毒问题的了解仍然有限。

主题

本文旨在描述患者、有毒物质和中毒的特征,并确定影响患者预后的风险因素。

方法

对摩洛哥抗中毒与药物警戒中心1981年至2007年记录的所有蓄意自我中毒病例进行回顾性研究。

结果

共识别出1130例自我中毒病例。平均年龄为25±10.1岁,性别比为0.4。对苯二胺是最常见的死亡原因(48例死亡),其次是盐酸(15例死亡)。研究发现,康复与女性青少年之间以及死亡与其他年龄组男性之间存在密切关系。研究还发现,使用对苯二胺的患者死亡可能性是使用其他物质患者的12倍(95%置信区间:7.4%-19.2%)。患有呼吸系统和心血管疾病的患者相对风险分别为9.8(95%置信区间:6.3%-16%)和3.6(95%置信区间:2.3%-5.7%)。在937例已知预后的病例中,89例死亡(9.5%)。

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