Achour Sanae, Rhalem Naima, Khattabi Asmae, Lofti Hayat, Mokhtari Abdelrhani, Soulaymani Abdelmajid, Turcant Alain, Bencheikh Rachida Soulaymani
Unité de Toxicologie, Laboratoire Central d'Analyses Médicales, CHU Hassan II et Faculté de Médecine et de Pharmacie de Fès, Maroc.
Therapie. 2012 Jan-Feb;67(1):53-8. doi: 10.2515/therapie/2012003. Epub 2012 Apr 11.
Peganum harmala L. is commonly used in traditional medicine in Morocco for its sedative and emmenagogue properties but expose to the risk of overdose and poisoning. The aim of our study was to analyze a series of 200 cases of poisoning collected in poison control and pharmacovigilance center of Morocco in order to describe the epidemiological, clinical, therapeutic features and outcome of patients and indicate the toxicity of this plant used primarily for therapeutic purposes.
This retrospective study performed over a period of twenty four years from January 1984 to December 2008.
The mean age of patients was 24.4±16.8 years with a female predominance (167 women against 33 men). Therapeutic circumstance was found in 32.5%, followed by suicide (28.5%) and abortion (13.5%). The symptomatology was dominated by neurological, gastrointestinal and cardiovascular signs respectively 34.4%, 31.9 % and 15.8%. The evolution has been specified in 114 cases, 7 deaths have been deplored with a fatality rate of 6.2%.
骆驼蓬在摩洛哥传统医学中因其镇静和通经作用而常用，但存在过量使用和中毒风险。我们研究的目的是分析在摩洛哥毒物控制和药物警戒中心收集的200例中毒病例系列，以描述患者的流行病学、临床、治疗特征及转归，并指出这种主要用于治疗目的的植物的毒性。
这项回顾性研究在1984年1月至2008年12月的24年期间进行。
患者的平均年龄为24.4±16.8岁，女性居多（167名女性对33名男性）。治疗情况占32.5%，其次是自杀（28.5%）和堕胎（13.5%）。症状以神经、胃肠和心血管体征为主，分别占34.4%、31.9%和15.8%。114例患者病情有明确进展，令人遗憾的是有7例死亡，病死率为6.2%。
