美国医学遗传学与基因组学学会（ACMG）关于偶发发现的建议在科学和伦理方面存在缺陷。 - Suppr

Suppr

超能文献

ACMG recommendations on incidental findings are flawed scientifically and ethically.

作者信息

Holtzman Neil A

出版信息

Genet Med. 2013 Sep;15(9):750-1. doi: 10.1038/gim.2013.96.

DOI:10.1038/gim.2013.96

PMID:24008255

Abstract

摘要

相似文献

ACMG recommendations on incidental findings are flawed scientifically and ethically.美国医学遗传学与基因组学学会（ACMG）关于偶发发现的建议在科学和伦理方面存在缺陷。

Genet Med. 2013 Sep;15(9):750-1. doi: 10.1038/gim.2013.96.

Points to consider for informed consent for genome/exome sequencing.基因组/外显子组测序知情同意需考虑的要点。

Genet Med. 2013 Sep;15(9):748-9. doi: 10.1038/gim.2013.94. Epub 2013 Aug 22.

Incidental findings in clinical genomics: a clarification.临床基因组学中的偶然发现：一项澄清

Genet Med. 2013 Aug;15(8):664-6. doi: 10.1038/gim.2013.82. Epub 2013 Jul 4.

Point-counterpoint. Ethics and genomic incidental findings.针锋相对。伦理学与基因组偶然发现

Science. 2013 May 31;340(6136):1047-8. doi: 10.1126/science.1240156. Epub 2013 May 16.

Minimizing liability risks under the ACMG recommendations for reporting incidental findings in clinical exome and genome sequencing.最小化 ACMG 建议中报告临床外显子组和基因组测序偶然发现的责任风险。

Genet Med. 2013 Dec;15(12):915-20. doi: 10.1038/gim.2013.135. Epub 2013 Sep 12.

Clinical tumor sequencing: an incidental casualty of the American College of Medical Genetics and Genomics recommendations for reporting of incidental findings.临床肿瘤测序：美国医学遗传学与基因组学学会关于报告偶发发现的建议的意外牺牲品。

J Clin Oncol. 2014 Jul 20;32(21):2203-5. doi: 10.1200/JCO.2013.54.8917. Epub 2014 Jun 23.

Are guidelines for genetic testing of children necessary?是否有必要为儿童制定基因检测指南？

Fam Cancer. 2010 Mar;9(1):23-5. doi: 10.1007/s10689-009-9278-0. Epub 2009 Aug 15.

Ethical issues: should we give the predictive genetic profile to the citizens?伦理问题：我们应该向公民提供预测性基因概况吗？

Clin Chem Lab Med. 2003 Apr;41(4):559-63. doi: 10.1515/CCLM.2003.085.

Ethical issues in genetic research: disclosure and informed consent.基因研究中的伦理问题：信息披露与知情同意

Nat Genet. 1997 Jan;15(1):16-20. doi: 10.1038/ng0197-16.

The new genetics: legal and ethical implications for medicine.新遗传学：医学的法律与伦理影响

Med J Aust. 1996 Sep 16;165(6):301-3. doi: 10.5694/j.1326-5377.1996.tb124983.x.

引用本文的文献

Exploring the motivations of research participants who chose not to learn medically actionable secondary genetic findings about themselves.探讨选择不了解自身具有医学可采取的二级遗传发现的研究参与者的动机。

Genet Med. 2021 Dec;23(12):2281-2288. doi: 10.1038/s41436-021-01271-1. Epub 2021 Jul 29.

Moving Toward Patient-Tailored Treatment in ALS and FTD: The Potential of Genomic Assessment as a Tool for Biological Discovery and Trial Recruitment.迈向肌萎缩侧索硬化症和额颞叶痴呆的个性化治疗：基因组评估作为生物学发现和试验招募工具的潜力

Front Neurosci. 2021 Mar 1;15:639078. doi: 10.3389/fnins.2021.639078. eCollection 2021.

Massively Parallel Sequencing for Rare Genetic Disorders: Potential and Pitfalls.大规模平行测序在罕见遗传病中的应用：潜在价值与陷阱。

Front Endocrinol (Lausanne). 2021 Feb 19;11:628946. doi: 10.3389/fendo.2020.628946. eCollection 2020.

Opportunistic genomic screening. Recommendations of the European Society of Human Genetics.机会性基因组筛查。欧洲人类遗传学学会的建议。

Eur J Hum Genet. 2021 Mar;29(3):365-377. doi: 10.1038/s41431-020-00758-w. Epub 2020 Nov 22.

Ethical values supporting the disclosure of incidental and secondary findings in clinical genomic testing: a qualitative study.支持在临床基因组检测中披露偶然和次要发现的伦理价值观：一项定性研究。

BMC Med Ethics. 2020 Jan 30;21(1):9. doi: 10.1186/s12910-020-0452-0.

Ethical Issues in Newborn Sequencing Research: The Case Study of BabySeq.新生儿测序研究中的伦理问题：以 BabySeq 为例。

Pediatrics. 2019 Dec;144(6). doi: 10.1542/peds.2019-1031. Epub 2019 Nov 12.

Criteria for reporting incidental findings in clinical exome sequencing - a focus group study on professional practices and perspectives in Belgian genetic centres.临床外显子测序中偶然发现报告标准 - 比利时遗传中心专业实践和观点的焦点小组研究。

BMC Med Genomics. 2019 Aug 20;12(1):123. doi: 10.1186/s12920-019-0561-0.

Ethical Issues in Contemporary Clinical Genetics.当代临床遗传学中的伦理问题。

Mayo Clin Proc Innov Qual Outcomes. 2018 May 8;2(2):81-90. doi: 10.1016/j.mayocpiqo.2018.03.005. eCollection 2018 Jun.

The Continuing Evolution of Ethical Standards for Genomic Sequencing in Clinical Care: Restoring Patient Choice.临床护理中基因组测序伦理标准的持续演变：恢复患者选择权。

J Law Med Ethics. 2017 Sep;45(3):333-340. doi: 10.1177/1073110517737531. Epub 2017 Oct 18.

Ethical Considerations Related to Return of Results from Genomic Medicine Projects: The eMERGE Network (Phase III) Experience.与基因组医学项目结果反馈相关的伦理考量：eMERGE 网络（第三阶段）经验

J Pers Med. 2018 Jan 3;8(1):2. doi: 10.3390/jpm8010002.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验