Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen (The Netherlands), Fax: (+31) 50-363-4296.
ChemSusChem. 2013 Sep;6(9):1774-8. doi: 10.1002/cssc.201300378. Epub 2013 Sep 5.
An efficient and simple method for selective oxidation of secondary alcohols and oxidation of alkanes to ketones is reported. An in situ prepared catalyst is employed based on manganese(II) salts, pyridine-2-carboxylic acid, and butanedione, which provides good-to-excellent conversions and yields with high turnover numbers (up to 10 000) with H2 O2 as oxidant at ambient temperatures. In substrates bearing multiple alcohol groups, secondary alcohols are converted to ketones selectively and, in general, benzyl C-H oxidation proceeds in preference to aliphatic C-H oxidation.
本文报道了一种高效、简便的选择性氧化仲醇和烷烃为酮的方法。该方法采用原位制备的催化剂，基于二价锰盐、吡啶-2-羧酸和丁二酮，在环境温度下以 H2 O2 为氧化剂，具有良好至优异的转化率和收率，周转数高达 10000。在含有多个醇基的底物中，仲醇选择性地转化为酮，并且通常，苄基 C-H 氧化优先于脂肪族 C-H 氧化。
