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在小型牙科手术中真的需要停止抗凝治疗吗?——那牙髓显微手术呢?

Is stopping of anticoagulant therapy really required in a minor dental surgery? - How about in an endodontic microsurgery?

作者信息

Cho Yong-Wook, Kim Euiseong

机构信息

Department of Conservative Dentistry, Yonsei University College of Dentistry, Seoul, Korea.

出版信息

Restor Dent Endod. 2013 Aug;38(3):113-8. doi: 10.5395/rde.2013.38.3.113. Epub 2013 Aug 23.

DOI:10.5395/rde.2013.38.3.113
PMID:24010076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3761118/
Abstract

Nowadays, oral anticoagulants are commonly prescribed to numerous patients for preventing cardiovascular accident such as thromboembolism. An important side effect of anticoagulant is anti-hemostasis. In a major surgery, the oral anticoagulant therapy (OAT) regimen must be changed before the surgery for proper post-operative bleeding control. However, in a minor dental surgery and endodontic surgery, the necessity for changing or discontinuing the OAT is open to debate. In this study, risks of the consequences were weighed and analyzed. In patients who stop the OAT, the occurrence of thromboembolic complication is rare but the result is fatal. In patients who continuing the OAT, post-operative bleeding can be controlled well with the local hemostatic measures. In the endodontic surgery, there are almost no studies about this issue. The intra-operative bleeding control is particularly important in the endodontic surgery because of its delicate and sensitive procedures such as inspection of resected root surface using dental microscope and retrograde filling. Further studies are necessary about this issue in the viewpoint of endodontic surgery.

摘要

如今,口服抗凝剂被广泛用于众多患者以预防心血管意外,如血栓栓塞。抗凝剂的一个重要副作用是抗凝血。在大手术中,术前必须改变口服抗凝治疗(OAT)方案以适当控制术后出血。然而,在小型牙科手术和牙髓手术中,改变或停用OAT的必要性存在争议。在本研究中,对后果的风险进行了权衡和分析。在停用OAT的患者中,血栓栓塞并发症的发生率很低,但后果是致命的。在继续OAT的患者中,通过局部止血措施可以很好地控制术后出血。在牙髓手术中,几乎没有关于这个问题的研究。由于牙髓手术过程精细且敏感,如使用牙科显微镜检查切除的牙根表面和逆行充填,术中出血控制尤为重要。从牙髓手术的角度来看,关于这个问题还需要进一步研究。

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本文引用的文献

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Restor Dent Endod. 2012 Nov;37(4):188-93. doi: 10.5395/rde.2012.37.4.188. Epub 2012 Nov 21.
2
How I treat anticoagulated patients undergoing an elective procedure or surgery.我如何治疗接受择期手术或手术的抗凝患者。
Blood. 2012 Oct 11;120(15):2954-62. doi: 10.1182/blood-2012-06-415943. Epub 2012 Aug 28.
3
Long-term outcome of the cases classified as successes based on short-term follow-up in endodontic microsurgery.基于短期随访的根管显微手术成功病例的长期疗效。
J Endod. 2012 Sep;38(9):1192-6. doi: 10.1016/j.joen.2012.06.014. Epub 2012 Jul 21.
4
Failure of setting of mineral trioxide aggregate in the presence of fetal bovine serum and its prevention.在胎牛血清存在的情况下,三氧化物聚合体的设置失败及其预防。
J Endod. 2012 Apr;38(4):536-40. doi: 10.1016/j.joen.2011.12.005. Epub 2012 Jan 9.
5
Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.抗栓治疗的围手术期管理:抗栓治疗与血栓预防,第 9 版:美国胸科医师学会循证临床实践指南。
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9
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10
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J Endod. 2011 Mar;37(3):316-20. doi: 10.1016/j.joen.2010.11.029. Epub 2011 Jan 8.