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小儿克罗恩病危及生命的下消化道出血

Life-threatening lower gastrointestinal hemorrhage in pediatric Crohn's disease.

作者信息

Kim Earl, Kang Yunkoo, Lee Mi Jung, Park Young Nyun, Koh Hong

机构信息

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. ; Severance Pediatric Liver Disease Research Group, Severance Children's Hospital, Seoul, Korea.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):53-60. doi: 10.5223/pghn.2013.16.1.53. Epub 2013 Mar 31.

Abstract

In Crohn's disease, mild gastrointestinal bleeding often occurs; however massive gastrointestinal hemorrhage, which can have a dramatic effect on a patient's vital sign, is rare. This could result in potentially life-threatening complications, which can lead to death. Massive hemorrhagic Crohn's disease is not well known and for this reason, they are a diagnostic and therapeutic challenge. Various diagnostic and therapeutic methods are currently being developed and used. The surgical method is often used only as a last measure since this approach has the risk of serious complications that may endanger patients. However, if massive bleeding continues even after all therapeutic methods are used, the surgical method must be implemented. In this case, all therapeutic methods were found to be ineffective; therefore, surgery was used as a last option. Ultimately, the surgical method was found to be successfully used to treat life-threatening hemorrhagic Crohn's disease.

摘要

在克罗恩病中,轻度胃肠道出血经常发生;然而,可对患者生命体征产生显著影响的大量胃肠道出血却很罕见。这可能导致潜在的危及生命的并发症,进而可能导致死亡。大量出血性克罗恩病并不为人所熟知,因此,它们是诊断和治疗上的挑战。目前正在研发和使用各种诊断和治疗方法。手术方法通常仅作为最后手段使用,因为这种方法有引发可能危及患者的严重并发症的风险。然而,如果在使用了所有治疗方法后仍持续大量出血,则必须实施手术方法。在这种情况下,发现所有治疗方法均无效;因此,手术被用作最后的选择。最终,发现手术方法成功用于治疗危及生命的出血性克罗恩病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/5b0a38dd87d9/pghn-16-53-g001.jpg

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