• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

小儿克罗恩病危及生命的下消化道出血

Life-threatening lower gastrointestinal hemorrhage in pediatric Crohn's disease.

作者信息

Kim Earl, Kang Yunkoo, Lee Mi Jung, Park Young Nyun, Koh Hong

机构信息

Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. ; Severance Pediatric Liver Disease Research Group, Severance Children's Hospital, Seoul, Korea.

出版信息

Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):53-60. doi: 10.5223/pghn.2013.16.1.53. Epub 2013 Mar 31.

DOI:10.5223/pghn.2013.16.1.53
PMID:24010107
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3746042/
Abstract

In Crohn's disease, mild gastrointestinal bleeding often occurs; however massive gastrointestinal hemorrhage, which can have a dramatic effect on a patient's vital sign, is rare. This could result in potentially life-threatening complications, which can lead to death. Massive hemorrhagic Crohn's disease is not well known and for this reason, they are a diagnostic and therapeutic challenge. Various diagnostic and therapeutic methods are currently being developed and used. The surgical method is often used only as a last measure since this approach has the risk of serious complications that may endanger patients. However, if massive bleeding continues even after all therapeutic methods are used, the surgical method must be implemented. In this case, all therapeutic methods were found to be ineffective; therefore, surgery was used as a last option. Ultimately, the surgical method was found to be successfully used to treat life-threatening hemorrhagic Crohn's disease.

摘要

在克罗恩病中,轻度胃肠道出血经常发生;然而,可对患者生命体征产生显著影响的大量胃肠道出血却很罕见。这可能导致潜在的危及生命的并发症,进而可能导致死亡。大量出血性克罗恩病并不为人所熟知,因此,它们是诊断和治疗上的挑战。目前正在研发和使用各种诊断和治疗方法。手术方法通常仅作为最后手段使用,因为这种方法有引发可能危及患者的严重并发症的风险。然而,如果在使用了所有治疗方法后仍持续大量出血,则必须实施手术方法。在这种情况下,发现所有治疗方法均无效;因此,手术被用作最后的选择。最终,发现手术方法成功用于治疗危及生命的出血性克罗恩病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/f3d0fc1f4db6/pghn-16-53-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/5b0a38dd87d9/pghn-16-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/56ac50f2a54e/pghn-16-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/63dd7fec556c/pghn-16-53-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/67d817056858/pghn-16-53-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/57155ddc2adb/pghn-16-53-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/f3d0fc1f4db6/pghn-16-53-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/5b0a38dd87d9/pghn-16-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/56ac50f2a54e/pghn-16-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/63dd7fec556c/pghn-16-53-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/67d817056858/pghn-16-53-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/57155ddc2adb/pghn-16-53-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bee/3746042/f3d0fc1f4db6/pghn-16-53-g006.jpg

相似文献

1
Life-threatening lower gastrointestinal hemorrhage in pediatric Crohn's disease.小儿克罗恩病危及生命的下消化道出血
Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):53-60. doi: 10.5223/pghn.2013.16.1.53. Epub 2013 Mar 31.
2
Acute lower gastrointestinal bleeding in Crohn's disease: characteristics of a unique series of 34 patients. Belgian IBD Research Group.克罗恩病中的急性下消化道出血:34例独特病例系列的特征。比利时炎症性肠病研究组
Am J Gastroenterol. 1999 Aug;94(8):2177-81. doi: 10.1111/j.1572-0241.1999.01291.x.
3
Life-threatening hemorrhage and exsanguination from Crohn's disease. Report of four cases.
Dis Colon Rectum. 1995 Jan;38(1):85-95. doi: 10.1007/BF02053865.
4
Crohn's disease with life-threatening hemorrhage from terminal ileum: successful control by superselective arterial embolization.克罗恩病伴回肠末端危及生命的出血:经超选择性动脉栓塞成功控制
J Gastroenterol. 2005 Dec;40(12):1155-7. doi: 10.1007/s00535-005-1714-9.
5
Severe gastrointestinal bleeding in Crohn's disease.
Ann Ital Chir. 2003 Mar-Apr;74(2):213-5; discussion 216.
6
A case of Crohn's disease with recurrent massive life-threatening hemorrhage from terminal ileum.一例克罗恩病患者回肠末端反复出现危及生命的大量出血。
Hepatogastroenterology. 1999 May-Jun;46(27):1695-8.
7
Massive gastrointestinal bleeding in Crohn's disease.克罗恩病中的大量胃肠道出血。
J R Soc Med. 1985 Aug;78(8):628-9. doi: 10.1177/014107688507800805.
8
Rare surgical complications of Crohn's disease. Clinical and therapeutic considerations.克罗恩病罕见的手术并发症。临床及治疗考量
Chir Ital. 2004 Jan-Feb;56(1):37-45.
9
Infliximab for severe recurrent Crohn's disease presenting with massive gastrointestinal hemorrhage.英夫利昔单抗用于治疗伴有大量胃肠道出血的重度复发性克罗恩病。
J Clin Gastroenterol. 2003 Mar;36(3):238-41. doi: 10.1097/00004836-200303000-00011.
10
[Life-threatening gastrointestinal bleeding in Crohn disease].[克罗恩病中危及生命的胃肠道出血]
Orv Hetil. 1998 Sep 20;139(38):2261-2.

引用本文的文献

1
Combining mechanistic modeling with machine learning as a strategy to predict inflammatory bowel disease clinical scores.将机械模型与机器学习相结合作为预测炎症性肠病临床评分的一种策略。
Front Pharmacol. 2025 Feb 25;16:1479666. doi: 10.3389/fphar.2025.1479666. eCollection 2025.
2
Hemorrhagic Shock Presenting as the First Manifestation of Inflammatory Stricturing Crohn's Disease.出血性休克作为炎症性狭窄型克罗恩病的首发表现
ACG Case Rep J. 2025 Jan 8;12(1):e01589. doi: 10.14309/crj.0000000000001589. eCollection 2025 Jan.
3
Accelerated Infliximab Induction for Severe Lower Gastrointestinal Bleeding in a Young Patient with Crohn's Disease: A Case Report.

本文引用的文献

1
Early treatment in Crohn's disease: do we have enough evidence to reverse the therapeutic pyramid?克罗恩病的早期治疗:我们是否有足够的证据来颠覆治疗金字塔?
J Gastrointestin Liver Dis. 2012 Mar;21(1):67-73.
2
[Guidelines for the management of Crohn's disease].[克罗恩病管理指南]
Korean J Gastroenterol. 2012 Feb;59(2):141-79. doi: 10.4166/kjg.2012.59.2.141.
3
Revisiting the past: intra-arterial vasopressin for severe gastrointestinal bleeding in Crohn's disease.重温过去:动脉内加压素治疗克罗恩病严重胃肠道出血。
英夫利昔单抗加速诱导治疗年轻克罗恩病患者严重下消化道出血:一例报告
World J Clin Cases. 2022 Jan 14;10(2):733-740. doi: 10.12998/wjcc.v10.i2.733.
4
Evidence-based clinical practice guidelines for inflammatory bowel disease 2020.2020 年炎症性肠病循证临床实践指南。
J Gastroenterol. 2021 Jun;56(6):489-526. doi: 10.1007/s00535-021-01784-1. Epub 2021 Apr 22.
J Crohns Colitis. 2010 Oct;4(4):479-82. doi: 10.1016/j.crohns.2010.02.011. Epub 2010 Mar 29.
4
Life-threatening jejunal hemorrhage as first presentation of Crohn's disease.危及生命的空肠出血作为克罗恩病的首发表现
Inflamm Bowel Dis. 2010 Aug;16(8):1277-8. doi: 10.1002/ibd.21182.
5
[Efficacy of infliximab in the treatment of korean patients with crohns disease].
Korean J Gastroenterol. 2009 Aug;54(2):108-16. doi: 10.4166/kjg.2009.54.2.108.
6
Infliximab for severe gastrointestinal bleeding in Crohn's disease.英夫利昔单抗治疗克罗恩病严重胃肠道出血
Inflamm Bowel Dis. 2009 Mar;15(3):483-4. doi: 10.1002/ibd.20635.
7
[Life-threatening acute lower gastrointestinal bleeding in patients with Crohn's disease].
Rev Esp Enferm Dig. 2007 Jul;99(7):388-91. doi: 10.4321/s1130-01082007000700004.
8
Operative management of small bowel Crohn's disease.小肠克罗恩病的手术治疗
Surg Clin North Am. 2007 Jun;87(3):587-610. doi: 10.1016/j.suc.2007.03.011.
9
Crohn's disease with life-threatening hemorrhage from terminal ileum: successful control by superselective arterial embolization.克罗恩病伴回肠末端危及生命的出血:经超选择性动脉栓塞成功控制
J Gastroenterol. 2005 Dec;40(12):1155-7. doi: 10.1007/s00535-005-1714-9.
10
[Effect of infliximab in the treatment of refractory inflammatory bowel disease with complication].英夫利昔单抗治疗合并并发症的难治性炎症性肠病的疗效
Korean J Gastroenterol. 2004 Nov;44(5):259-66.