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社区如何塑造蛋白质数据库。

How community has shaped the Protein Data Bank.

机构信息

RCSB PDB, Center for Integrative Proteomics Research and Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ USA 08854.

出版信息

Structure. 2013 Sep 3;21(9):1485-91. doi: 10.1016/j.str.2013.07.010.

Abstract

Following several years of community discussion, the Protein Data Bank (PDB) was established in 1971 as a public repository for the coordinates of three-dimensional models of biological macromolecules. Since then, the number, size, and complexity of structural models have continued to grow, reflecting the productivity of structural biology. Managed by the Worldwide PDB organization, the PDB has been able to meet increasing demands for the quantity of structural information and of quality. In addition to providing unrestricted access to structural information, the PDB also works to promote data standards and to raise the profile of structural biology with broader audiences. In this perspective, we describe the history of PDB and the many ways in which the community continues to shape the archive.

摘要

经过多年的社区讨论,蛋白质数据库(PDB)于 1971 年成立,作为生物大分子三维模型坐标的公共存储库。从那时起,结构模型的数量、大小和复杂性不断增加,反映了结构生物学的生产力。由全球 PDB 组织管理,PDB 能够满足对结构信息数量和质量的不断增长的需求。除了提供对结构信息的无限制访问外,PDB 还致力于促进数据标准的制定,并提高更广泛受众对结构生物学的认识。在这个角度上,我们描述了 PDB 的历史以及社区继续塑造档案的多种方式。

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