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腹主动脉瘤在南欧某些地区的患病率仍然很高。

Prevalence of abdominal aortic aneurysm is still high in certain areas of southern Europe.

作者信息

Barba Ángel, Vega de Céniga Melina, Estallo Luis, de la Fuente Natalia, Viviens Belén, Izagirre Maite

机构信息

Department of Angiology and Vascular Surgery, Hospital de Galdakao-Usansolo, Biscay, Spain.

出版信息

Ann Vasc Surg. 2013 Nov;27(8):1068-73. doi: 10.1016/j.avsg.2013.01.017. Epub 2013 Sep 5.

Abstract

BACKGROUND

Ultrasound screening of abdominal aortic aneurysm (AAA) has proved to reduce mortality from AAA rupture and has been implemented in several countries. Recent reports show a decreasing prevalence of AAA in Western countries. We report the results from a screening program among 65-year-old men in a defined area in the North of Spain.

METHODS

We invited the 1,413 men born in 1943 and registered in the health area under our care to participate in the study. We registered their medical history and cardiovascular risk factors and we performed an abdominal ultrasound scan. We diagnosed an AAA when the infrarenal aortic diameter was ≥3 cm. We performed univariate and multivariate analysis to assess independent factors associated with the development of an AAA, using logistic regression.

RESULTS

The participation rate was 70.8%. The prevalence of active smoking, hypertension, diabetes, and hypercholesterolemia was 19.6%, 52.1%, 25.7%, and 76.9%, respectively. Including 3 previously known and repaired AAAs, the total prevalence of AAA was 4.7% (n=37). The mean diameter of the AAA was 35.7±7.9 mm (range, 30-62 mm). Multivariate analysis confirmed the independent impact of active smoking (Exp[B], 3.47 [95% confidence interval {CI}: 1.67-7.22]), hypertension (Exp[B], 2.43 [95% CI: 1.08-5.45]), and peripheral arterial disease (Exp[B], 3.00 [95% CI: 1.16-7.80]) on the incidence of AAA.

CONCLUSIONS

The prevalence of AAA remains high in the studied area in the North of Spain. The potential benefit of lowering smoking rates has not been observed yet. The current international recommendations of screening for 65-year-old men are still applicable in our population.

摘要

背景

超声筛查腹主动脉瘤(AAA)已被证明可降低AAA破裂导致的死亡率,并已在多个国家实施。最近的报告显示西方国家AAA的患病率在下降。我们报告了西班牙北部一个特定地区65岁男性筛查项目的结果。

方法

我们邀请了1943年出生且在我们负责的健康区域登记的1413名男性参与研究。我们记录了他们的病史和心血管危险因素,并进行了腹部超声扫描。当肾下腹主动脉直径≥3 cm时,我们诊断为AAA。我们使用逻辑回归进行单变量和多变量分析,以评估与AAA发生相关的独立因素。

结果

参与率为70.8%。当前吸烟、高血压、糖尿病和高胆固醇血症的患病率分别为19.6%、52.1%、25.7%和76.9%。包括3例先前已知并已修复的AAA,AAA的总患病率为4.7%(n = 37)。AAA的平均直径为35.7±7.9 mm(范围30 - 62 mm)。多变量分析证实了当前吸烟(Exp[B],3.47 [95%置信区间{CI}:1.67 - 7.22])、高血压(Exp[B],2.43 [95% CI:1.08 - 5.45])和外周动脉疾病(Exp[B],3.00 [95% CI:1.16 - 7.80])对AAA发病率的独立影响。

结论

在西班牙北部的研究区域,AAA的患病率仍然很高。尚未观察到降低吸烟率的潜在益处。目前国际上对65岁男性进行筛查的建议在我们的人群中仍然适用。

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