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筛查 70 岁男性的腹主动脉瘤时,患病率低于预期。

Lower prevalence than expected when screening 70-year-old men for abdominal aortic aneurysm.

机构信息

Department of Cardiovascular Surgery, University Hospital, Linköping, Sweden; Division of Cardiovascular Medicine, University Hospital, Linköping, Sweden.

出版信息

Eur J Vasc Endovasc Surg. 2013 Oct;46(4):453-9. doi: 10.1016/j.ejvs.2013.07.014. Epub 2013 Aug 23.

Abstract

BACKGROUND

Screening 65-year-old men for abdominal aortic aneurysms (AAA) is a cost-effective method to reduce the mortality from ruptured AAA. However, contemporary results show a lower than expected prevalence of AAA, thus questioning the benefit of screening. Since the prevalence increases with age, a possible way to enhance the benefit of screening might be to screen older men. Our aim was to determine the contemporary screening-detected prevalence among 70-year-old men.

METHODS

A total of 5,623 unscreened 70-year-old men were invited to ultrasound screening. Uni- and multivariable analyses were used to assess the risk factors for AAA.

RESULTS

The attendance rate was 84.0%. The prevalence of previously unknown AAAs was 2.3%. When adding the 64 men with an already known AAA to the screening-detected ones, the total prevalence in the population was at least 3.0%, and the previously discovered AAAs constituted 37.4% of the total prevalence. "Ex smoker" and "Current smoker" were the most important risk factors.

CONCLUSIONS

When screening 70-year-old men for AAA, the prevalence was less than half that expected, despite a high attendance rate. Smoking was the strongest risk factor. Almost 40% of the men with AAAs were already known from other means than screening.

摘要

背景

对 65 岁男性进行腹主动脉瘤(AAA)筛查是降低 AAA 破裂死亡率的一种具有成本效益的方法。然而,目前的结果显示 AAA 的患病率低于预期,因此对筛查的益处提出了质疑。由于患病率随年龄的增加而增加,提高筛查益处的一种可能方法是对老年男性进行筛查。我们的目的是确定 70 岁男性的筛查检出患病率。

方法

共邀请 5623 名未经筛查的 70 岁男性进行超声筛查。采用单变量和多变量分析来评估 AAA 的危险因素。

结果

出勤率为 84.0%。先前未知的 AAA 的患病率为 2.3%。将 64 名已有已知 AAA 的男性纳入筛查检出的患者后,人群中的总患病率至少为 3.0%,先前发现的 AAA 占总患病率的 37.4%。“前吸烟者”和“当前吸烟者”是最重要的危险因素。

结论

尽管出勤率很高,但对 70 岁男性进行 AAA 筛查的患病率仍不到预期的一半。吸烟是最强的危险因素。近 40%的 AAA 患者已经通过筛查以外的其他手段得知。

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