第四脑室原发性大 B 细胞淋巴瘤。
Primary large B-cell lymphoma of the fourth ventricle.
机构信息
Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, Taipei 112, Taiwan, ROC.
Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; National Yang Ming University School of Medicine, Taipei, Taiwan, ROC.
出版信息
J Clin Neurosci. 2014 Jan;21(1):180-3. doi: 10.1016/j.jocn.2013.02.036. Epub 2013 Sep 5.
We present a patient with an isolated primary central nervous system lymphoma (PCNSL) of the fourth ventricle. A 77-year-old man had a 1 week history of intermittent vertigo, nausea, vomiting, and progressively unsteady gait. CT scans of the brain showed a fourth ventricle tumor. MRI revealed a 2.5 cm dumbbell-shaped avidly-enhancing tumor in the fourth ventricle. Metastasis or high-grade glioma was suspected. The neuropathological findings were compatible with a diffuse large B-cell lymphoma. A slit lamp examination, bone marrow biopsy, and imaging studies for extracranial lesions were unremarkable. We suggest that PCNSL be listed in the differential diagnosis of fourth ventricle tumors with well-circumscribed margins and homogenous contrast enhancement.
我们报告一例第四脑室孤立性原发性中枢神经系统淋巴瘤（PCNSL）患者。一名 77 岁男性，间断性眩晕 1 周，伴恶心、呕吐，行走不稳进行性加重。颅脑 CT 显示第四脑室肿瘤。MRI 显示第四脑室 2.5cm 哑铃状强化肿瘤。考虑转移瘤或高级别胶质瘤。神经病理学检查符合弥漫性大 B 细胞淋巴瘤。裂隙灯、骨髓活检和颅外病变影像学检查均未见异常。我们建议将 PCNSL 列入边界清楚、均匀强化的第四脑室肿瘤的鉴别诊断中。
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