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第四脑室神经鞘瘤:第八例报告

Schwannoma of the Fourth Ventricle: The Eighth Case Report.

作者信息

Santos Maria M, Timóteo Ângela, Coiteiro Domingos, Pimentel José

机构信息

Department of Neurological Surgery, Centro Hospitalar Lisboa Norte, Entidade Pública Empresarial, Lisbon, Portugal.

Department of Neurology, Hospital Fernando Fonseca, Amadora, Portugal.

出版信息

World Neurosurg. 2015 Nov;84(5):1493.e9-13. doi: 10.1016/j.wneu.2015.04.036. Epub 2015 Apr 25.

Abstract

OBJECTIVE

We report an uncommon case of a surgical resection of a fourth ventricle tumor in an adult that proved to be a schwannoma.

METHODS

A 53-year-old man presented with a 1.5-year history of gait unsteadiness and vertigo and a few-week history of headache, emesis, and neurogenic dysphagia. A brain magnetic resonance imaging revealed a large, heterogeneously contrast enhancing mass located within the fourth ventricle, compressing the brainstem and causing supratentorial ventricle enlargement. A suboccipital craniotomy and a telovelar approach were performed to resect the tumor. The ventricular system was repermeabilized at the end of the operation.

RESULTS

A postoperative magnetic resonance imaging confirmed complete tumor removal. There was an initial worsening of the preoperative deficits, which progressively improved. The tumor was classified as a fourth ventricle schwannoma. There has been no evidence of tumor recurrence during the 6 years of follow-up. At present, the patient is ambulatory and reports an intermittent diplopia on conjugated gaze.

CONCLUSION

This case report intends to reveal the eighth case of a fourth ventricle schwannoma since 1957. Schwannomas of the fourth ventricle are infrequent but should be accounted in the differential diagnosis of space-occupying lesions in this location. Gross total resection might be the definite treatment of these tumors if deemed possible.

摘要

目的

我们报告一例罕见的成年患者第四脑室肿瘤手术切除病例,术后病理证实为神经鞘瘤。

方法

一名53岁男性,有1.5年步态不稳和眩晕病史,以及几周的头痛、呕吐和神经性吞咽困难病史。脑部磁共振成像显示第四脑室内有一个大的、不均匀强化的肿块,压迫脑干并导致幕上脑室扩大。采用枕下开颅术和经小脑幕下入路切除肿瘤。手术结束时恢复脑室系统通畅。

结果

术后磁共振成像证实肿瘤完全切除。术前的神经功能缺损最初有所加重,但随后逐渐改善。肿瘤被分类为第四脑室神经鞘瘤。在6年的随访中没有肿瘤复发的证据。目前,患者可独立行走,报告在共轭凝视时有间歇性复视。

结论

本病例报告旨在揭示自1957年以来第四脑室神经鞘瘤的第八例病例。第四脑室神经鞘瘤并不常见,但在该部位占位性病变的鉴别诊断中应予以考虑。如果可能,全切除可能是这些肿瘤的确定性治疗方法。

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