Department of Pathology and Immunology at Washington University School of Medicine, St. Louis, Missouri, USA.
Nat Med. 2013 Sep;19(9):1094-5. doi: 10.1038/nm.3316.
Macrophages accumulate in atherosclerotic lesions during the inflammation that is part of atherosclerosis development and progression. A new study in mice indicates that the accumulation of macrophages in atherosclerotic plaques depends on local macrophage proliferation rather than the recruitment of circulating monocytes.
巨噬细胞在动脉粥样硬化发展和进展过程中的炎症中积聚在动脉粥样硬化病变中。一项新的小鼠研究表明，动脉粥样硬化斑块中巨噬细胞的积累依赖于局部巨噬细胞增殖，而不是循环单核细胞的募集。
