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该停止还是“去囊肿化”?胰腺囊性病变的评估与管理

To cease or 'de-cyst'? The evaluation and management of pancreatic cystic lesions.

作者信息

Enestvedt Brintha K, Ahmad Nuzhat

机构信息

Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, L461, Portland, OR 97239, USA.

出版信息

Curr Gastroenterol Rep. 2013 Oct;15(10):348. doi: 10.1007/s11894-013-0348-y.

DOI:10.1007/s11894-013-0348-y
PMID:24014118
Abstract

Due to the widespread use of cross-sectional imaging and advances in imaging technology, pancreatic cystic lesions are increasingly being detected. The diagnosis and management of such cysts remains challenging and continues to evolve. Different pancreatic cyst types have varying malignant potential. Thus, accurate cyst characterization is essential to appropriate management; the most clinically important distinction is differentiating mucinous lesions, which have malignant potential and may benefit from surgical resection, from non-mucinous cystic lesions. Endoscopic ultrasound with fine needle aspiration with cytologic, chemical,, and tumor marker analysis appears to be the best currently available method for accurately characterizing a cyst's malignant potential, and therefore impacts the most important management decision for a pancreatic cyst-continued surveillance or surgical resection.

摘要

由于横断面成像的广泛应用和成像技术的进步,胰腺囊性病变的检出率越来越高。此类囊肿的诊断和管理仍然具有挑战性,并且仍在不断发展。不同类型的胰腺囊肿具有不同的恶性潜能。因此,准确的囊肿特征描述对于恰当的管理至关重要;临床上最重要的区别是区分具有恶性潜能且可能从手术切除中获益的黏液性病变与非黏液性囊性病变。带有细针穿刺并进行细胞学、化学和肿瘤标志物分析的内镜超声似乎是目前可用于准确描述囊肿恶性潜能的最佳方法,因此影响着胰腺囊肿最重要的管理决策——继续监测还是手术切除。

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本文引用的文献

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Pancreas. 2013 May;42(4):717-21. doi: 10.1097/MPA.0b013e3182883a91.
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Cyst features and risk of malignancy in intraductal papillary mucinous neoplasms of the pancreas: a meta-analysis.胰腺导管内乳头状黏液性肿瘤的囊特征与恶性肿瘤风险:一项荟萃分析。
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Revised international consensus guidelines for the management of patients with mucinous cysts.
内镜超声、计算机断层扫描和磁共振成像对胰腺囊性病变的比较
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黏液性囊肿患者管理的修订国际共识指南
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