Sathyanarayana Hemavathi, Rani Leela, Rajendran R, Sarmah Pooja
Department of Microbiology, Sapthagiri Institute of Medical Sciences and Research Center, Bangalore, India.
J Lab Physicians. 2013 Jan;5(1):58-9. doi: 10.4103/0974-2727.115924.
Injection site abscess is an iatrogenic infection. Intramuscular (IM) injection is a common route to administer medication. Microorganisms known to cause injection site abscess are Staphylococcus aureus, Pseudomonas, Klebsiella, Escherichia coli commonly, Atypical mycobacteria, Clostridium species rarely. Gas gangrene is a necrotic infection of soft tissue with high mortality, often necessitating amputation in order to control the infection. Here, presenting a case of gas gangrene in a 19-year-old healthy male, who developed a life-threatening infection after IM injection of sodium diclofenac. Prompt clinical diagnosis, laboratory support, and timely surgical intervention saved the patient's life.
注射部位脓肿是一种医源性感染。肌内注射是常用的给药途径。已知可引起注射部位脓肿的微生物常见的有金黄色葡萄球菌、铜绿假单胞菌、克雷伯菌、大肠杆菌，少见的有非典型分枝杆菌、梭状芽孢杆菌。气性坏疽是一种软组织坏死性感染，死亡率高，常需截肢以控制感染。在此，报告一例19岁健康男性发生气性坏疽的病例，该患者在肌内注射双氯芬酸钠后发生了危及生命的感染。及时的临床诊断、实验室支持及适时的手术干预挽救了患者的生命。
