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绿茶和维生素 E 可增强运动对老年人身体成分、葡萄糖稳态和抗氧化状态的有益影响。

Green tea and vitamin E enhance exercise-induced benefits in body composition, glucose homeostasis, and antioxidant status in elderly men and women.

机构信息

Department of Anatomy and Cell Biology , Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

出版信息

J Am Coll Nutr. 2013;32(1):31-40. doi: 10.1080/07315724.2013.767661.

DOI:10.1080/07315724.2013.767661
PMID:24015697
Abstract

OBJECTIVE

To investigate the effects of green tea plus vitamin E in addition to exercise on body composition and metabolic and antioxidant parameters in healthy elderly individuals.

DESIGN

Interventional randomized controlled prospective trial.

METHODS

For 12 weeks, 22 elderly men and women (age: 71.1 ± 1.2 years; body mass index: 28.3 ± 0.5 kg/m(2) [mean ± SE]) undertook 30 minutes of moderately intense walking 6 d/wk. They were randomly assigned to ingest either green tea plus vitamin E (GTVE; 3 cups and 400 IU, respectively; n = 11) or placebo (n = 11). Data on anthropometrics, fasting insulin and glucose levels, physical fitness, dietary intake, safety parameters, and biomarkers of oxidation status were recorded and analyzed at the start and end of the study.

RESULTS

Though dietary intake was unchanged, improved exercise capacity was followed by a significant reduction in body weight and fasting insulin levels in all participants. Additional consumption of GTVE resulted in a twofold increase in serum vitamin E (from 20.4 to 40.6 μmol/L, p < 0.001) and a decrease of men's and women's waist circumferences (from 100.8 and 95.7 to 96.9 and 85.0 cm, p < 0.05 and p < 0.01, respectively) and fasting glucose levels (from 5.30 to 4.98 mmol/L, p < 0.01). Plasma protein carbonyls dropped (from 0.93 to 0.77 nmol/mg protein, p < 0.05), whereas erythrocyte catalase activities increased (from 26.7 to 29.7 U/g hemoglobin, p < 0.05) in the GTVE group only. Oral peroxidase activities were increased in both groups.

CONCLUSIONS

A daily dose of GTVE in healthy elderly men and women may improve exercise-induced benefits in body composition and glucose tolerance and may also lower oxidative burden.

摘要

目的

研究绿茶加维生素 E 补充剂联合运动对健康老年人身体成分及代谢和抗氧化参数的影响。

设计

干预性随机对照前瞻性试验。

方法

22 名健康老年人(男/女:71.1±1.2 岁;体重指数:28.3±0.5kg/m²),每周 6 天进行 30 分钟的适度强度步行运动。他们被随机分配至摄入绿茶加维生素 E(GTVE;分别为 3 杯和 400IU;n=11)或安慰剂(n=11)组。在研究开始和结束时记录并分析了人体测量学、空腹胰岛素和血糖水平、身体适应性、饮食摄入、安全性参数和氧化状态生物标志物的数据。

结果

尽管饮食摄入没有改变,但运动能力的提高导致所有参与者的体重和空腹胰岛素水平显著下降。额外补充 GTVE 使血清维生素 E 增加了两倍(从 20.4 增至 40.6μmol/L,p<0.001),并降低了男性和女性的腰围(从 100.8 和 95.7cm 降至 96.9 和 85.0cm,p<0.05 和 p<0.01)和空腹血糖水平(从 5.30 降至 4.98mmol/L,p<0.01)。仅在 GTVE 组中,血浆蛋白羰基下降(从 0.93 降至 0.77nmol/mg 蛋白,p<0.05),而红细胞过氧化氢酶活性增加(从 26.7 增至 29.7U/g 血红蛋白,p<0.05)。两组的口服过氧化物酶活性均增加。

结论

健康老年人每日补充 GTVE 可增强运动引起的身体成分和葡萄糖耐量的改善作用,还可能降低氧化应激。

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