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《东南亚营养调查(SEANUTS)设计:一项四国共病率的多阶段聚类设计研究》。

Design of the South East Asian Nutrition Survey (SEANUTS): a four-country multistage cluster design study.

机构信息

FrieslandCampina, Amersfoort, The Netherlands.

出版信息

Br J Nutr. 2013 Sep;110 Suppl 3:S2-10. doi: 10.1017/S0007114513002067.

DOI:10.1017/S0007114513002067
PMID:24016763
Abstract

Nutrition is a well-known factor in the growth, health and development of children. It is also acknowledged that worldwide many people have dietary imbalances resulting in over- or undernutrition. In 2009, the multinational food company FrieslandCampina initiated the South East Asian Nutrition Survey (SEANUTS), a combination of surveys carried out in Indonesia, Malaysia, Thailand and Vietnam, to get a better insight into these imbalances. The present study describes the general study design and methodology, as well as some problems and pitfalls encountered. In each of these countries, participants in the age range of 0·5-12 years were recruited according to a multistage cluster randomised or stratified random sampling methodology. Field teams took care of recruitment and data collection. For the health status of children, growth and body composition, physical activity, bone density, and development and cognition were measured. For nutrition, food intake and food habits were assessed by questionnaires, whereas in subpopulations blood and urine samples were collected to measure the biochemical status parameters of Fe, vitamins A and D, and DHA. In Thailand, the researchers additionally studied the lipid profile in blood, whereas in Indonesia iodine excretion in urine was analysed. Biochemical data were analysed in certified laboratories. Study protocols and methodology were aligned where practically possible. In December 2011, data collection was finalised. In total, 16,744 children participated in the present study. Information that will be very relevant for formulating nutritional health policies, as well as for designing innovative food and nutrition research and development programmes, has become available.

摘要

营养是儿童成长、健康和发育的一个众所周知的因素。全世界也有许多人存在饮食失衡,导致营养过剩或不足。2009 年,跨国食品公司菲仕兰(FrieslandCampina)发起了东南亚营养调查(SEANUTS),这是在印度尼西亚、马来西亚、泰国和越南进行的一系列调查的组合,以更好地了解这些失衡情况。本研究描述了一般研究设计和方法,以及遇到的一些问题和陷阱。在这些国家中的每一个国家,都按照多阶段聚类随机或分层随机抽样方法招募了 0.5-12 岁的参与者。现场小组负责招募和数据收集。对于儿童的健康状况、生长和身体成分、身体活动、骨密度以及发育和认知,都进行了测量。对于营养,通过问卷评估了食物摄入量和饮食习惯,而在亚人群中采集了血液和尿液样本,以测量铁、维生素 A 和 D 以及 DHA 的生化状态参数。在泰国,研究人员还研究了血液中的脂质谱,而在印度尼西亚,则分析了尿液中的碘排泄量。生化数据在经过认证的实验室进行分析。研究方案和方法在实际可行的情况下进行了调整。2011 年 12 月,数据收集工作完成。总共有 16744 名儿童参加了本研究。这些信息对于制定营养健康政策以及设计创新的食品和营养研究与开发计划非常重要。

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