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缺血性心肌病治疗的手术选择。

Surgical options for the management of ischemic cardiomyopathy.

作者信息

Michler Robert

机构信息

Montefiore Medical Center, Albert Einstein College of Medicine, New York City, NY, USA,

出版信息

Curr Treat Options Cardiovasc Med. 2013 Oct;15(5):518-32. doi: 10.1007/s11936-013-0261-6.

Abstract

Novel surgical alternatives and the refinement of conventional surgical therapies for the treatment of ischemic cardiomyopathy are in constant evolution. Current approaches involve the determined application of the appropriateness criteria for CABG surgery, the extension of mitral valve repair to complex patients with ischemic cardiomyopathy, finding appropriate patients who might benefit from surgical ventricular reconstruction, and surgical attempts to regenerate lost or damaged myocardium with transplanted stem cells. The refinement of surgical techniques and the medical optimization of candidates for surgery remain a cornerstone of management for patients with complex heart disease like ischemic cardiomyopathy. The horizon is bright for patients suffering from this condition and concentrated research efforts by groups such as the NHLBI-sponsored Cardiothoracic Surgery Network will have a major impact on the future of patients with heart disease.

摘要

用于治疗缺血性心肌病的新型手术替代方案以及传统手术疗法的改进一直在不断发展。当前的方法包括确定应用冠状动脉旁路移植术(CABG)手术的适用性标准、将二尖瓣修复扩展至患有缺血性心肌病的复杂患者、寻找可能从手术性心室重建中获益的合适患者,以及尝试用移植干细胞对丢失或受损的心肌进行手术再生。手术技术的改进以及手术候选者的医学优化仍然是缺血性心肌病等复杂心脏病患者管理的基石。对于患有这种疾病的患者来说前景光明,像美国国立心肺血液研究所(NHLBI)赞助的心胸外科手术网络等团队集中开展的研究工作将对心脏病患者的未来产生重大影响。

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