Hagiyama Y, Hashimoto H, Hamada K, Matsubara K, Fujioka T, Nawa A
Department of Obstetrics and Gynecology, Ehime University Graduate School of Medicine, Toh-on, Ehime, Japan.
Eur J Gynaecol Oncol. 2013;34(4):332-5.
Embryonal rhabdomyosarcoma (RMS) is a rare sarcoma that characteristically occurs in children. The current treatment protocols are based on trials performed in patients under 21 years of age. Embryonal RMS in women over 20 years of age is rare, and studies on treatments and outcomes are limited. The authors here in report a case of a 35-year-old woman with ectocervical RMS who was treated with radical hysterectomy followed by chemotherapy. She is currently disease-free. Based on a literature review, the authors recommend a surgical approach in combination with chemotherapy for treatment of embryonal RMS in adult patients.
胚胎性横纹肌肉瘤（RMS）是一种罕见的肉瘤，典型地发生于儿童。当前的治疗方案基于在21岁以下患者中进行的试验。20岁以上女性的胚胎性RMS罕见，关于治疗和预后的研究有限。本文作者报告了一例35岁患有宫颈外胚胎性RMS的女性患者，该患者接受了根治性子宫切除术后化疗。她目前无疾病。基于文献综述，作者推荐手术方法联合化疗用于治疗成年患者的胚胎性RMS。
