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饮酒的HIV阳性成年人中的粮食不安全与抗逆转录病毒治疗依从性

Food insecurity and antiretroviral adherence among HIV positive adults who drink alcohol.

作者信息

Kalichman Seth C, Grebler Tamar, Amaral Christina M, McKerney Megan, White Denise, Kalichman Moira O, Cherry Chauncey, Eaton Lisa

出版信息

J Behav Med. 2014 Oct;37(5):1009-18. doi: 10.1007/s10865-013-9536-3.

Abstract

Food insecurity is associated with HIV treatment non-adherence and poor health outcomes for people living with HIV/AIDS. Given the poor nutritional status common to people who drink alcohol, food insecurity may be particularly problematic for HIV positive individuals who drink alcohol. To examine food insecurity among HIV positive men and women who drink alcohol and its association with antiretroviral therapy (ART) adherence, health outcomes and health service utilization. Adults living with HIV (N = 183) in Atlanta, Georgia who reported alcohol use in the previous week and were receiving ART participated in a 12-month cohort. Participants were recruited from infectious disease clinics and social services to complete computerized interviews, monthly-unannounced pill counts to monitor ART adherence, and daily cell-phone delivered interactive-text assessments for alcohol use. Forty-three percent of participants experienced food insecurity during at least one month of the study period. Food insecurity was independently associated with suboptimal ART adherence and less suppressed HIV viral load over. Individuals who experienced food insecurity also had histories of more medical and psychiatric hospitalizations, and greater mental health problems. Food insecurity is prevalent among alcohol using people receiving ART and food insecurity is associated with treatment non-adherence, poor health outcomes, and increased medical and psychiatric hospitalizations.

摘要

粮食不安全与艾滋病毒感染者的艾滋病毒治疗不依从性及不良健康结局相关。鉴于饮酒者普遍存在营养状况不佳的情况,对于饮酒的艾滋病毒阳性个体而言,粮食不安全可能尤其成问题。为了调查饮酒的艾滋病毒阳性男性和女性中的粮食不安全情况及其与抗逆转录病毒疗法(ART)依从性、健康结局和卫生服务利用的关联。佐治亚州亚特兰大市183名报告前一周饮酒且正在接受抗逆转录病毒治疗的艾滋病毒感染者参与了一项为期12个月的队列研究。参与者从传染病诊所和社会服务机构招募,以完成计算机化访谈、每月不事先通知的药丸计数以监测抗逆转录病毒疗法的依从性,以及通过手机每日发送的关于饮酒情况的交互式文本评估。43%的参与者在研究期间至少有一个月经历了粮食不安全。粮食不安全与抗逆转录病毒疗法依从性欠佳及艾滋病毒病毒载量抑制不足独立相关。经历粮食不安全的个体也有更多的医疗和精神科住院史,以及更严重的心理健康问题。在接受抗逆转录病毒治疗的饮酒者中,粮食不安全情况普遍存在,且粮食不安全与治疗不依从、不良健康结局以及医疗和精神科住院次数增加相关。

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