Pellowski Jennifer A, Kalichman Seth C, Cherry Sabrina, Conway-Washington Christopher, Cherry Chauncey, Grebler Tamar, Krug Larissa
Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Department of Psychology, University of Connecticut, Storrs, CT, USA.
Ann Behav Med. 2016 Dec;50(6):844-853. doi: 10.1007/s12160-016-9812-x.
Limited access to resources can significantly impact health behaviors. Previous research on food insecurity and HIV has focused on establishing the relationship between lacking access to nutritious food and antiretroviral (ARV) medication non-adherence in a variety of social contexts.
This study aims to determine if several aspects of food insecurity co-occur with missed doses of medication on a daily basis among a sample of people living with HIV who have recently experienced hunger.
The current study utilized a prospective, observational design to test the daily relationship between food insecurity and medication non-adherence. Participants were followed for 45 days and completed daily assessments of food insecurity and alcohol use via interactive text message surveys and electronic medication adherence monitoring using the Wisepill.
Fifty-nine men and women living with HIV contributed a total of 2,655 days of data. Results showed that severe food insecurity (i.e., hunger), but not less severe food insecurity (i.e., worrying about having food), significantly predicted missed doses of medication on a daily level. Daily alcohol use moderated this relationship in an unexpected way; when individuals were hungry and drank alcohol on a given day, they were less likely to miss a dose of medication.
Among people living with HIV with recent experiences of hunger, this study demonstrates that there is a daily relationship between hunger and non-adherence to antiretroviral therapy. Future research is needed to test interventions designed to directly address the daily relationship between food insecurity and medication non-adherence.
资源获取受限会对健康行为产生重大影响。先前关于粮食不安全与艾滋病毒的研究主要集中在各种社会背景下,探讨获取营养食品困难与抗逆转录病毒(ARV)药物治疗依从性之间的关系。
本研究旨在确定在最近经历过饥饿的艾滋病毒感染者样本中,粮食不安全的几个方面是否与每日漏服药物情况同时出现。
本研究采用前瞻性观察设计,以测试粮食不安全与药物治疗不依从之间的日常关系。对参与者进行了45天的跟踪,并通过交互式短信调查以及使用Wisepill进行电子药物治疗依从性监测,完成对粮食不安全和饮酒情况的每日评估。
59名艾滋病毒感染者共提供了2655天的数据。结果显示,严重粮食不安全(即饥饿)而非不太严重的粮食不安全(即担心食物问题)能显著预测每日漏服药物的情况。每日饮酒以一种意想不到的方式调节了这种关系;当个体在某一天饥饿且饮酒时,他们漏服一剂药物的可能性较小。
在最近经历过饥饿的艾滋病毒感染者中,本研究表明饥饿与抗逆转录病毒治疗不依从之间存在日常关系。未来需要开展研究,以测试旨在直接解决粮食不安全与药物治疗不依从之间日常关系的干预措施。