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The effects of high concentrations of vitamin C on cancer cells.
Nutrients. 2013 Sep 9;5(9):3496-505. doi: 10.3390/nu5093496.
2
L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms.
Int J Biochem Cell Biol. 2004 Nov;36(11):2180-95. doi: 10.1016/j.biocel.2004.04.005.
4
Cytotoxic effects of high concentrations of sodium ascorbate on human myeloid cell lines.
Ann Hematol. 2015 Nov;94(11):1807-16. doi: 10.1007/s00277-015-2464-2. Epub 2015 Aug 12.
5
Vitamin C prevents DNA mutation induced by oxidative stress.
J Biol Chem. 2002 May 10;277(19):16895-9. doi: 10.1074/jbc.M201151200. Epub 2002 Mar 7.
6
Vitamin C-induced loss of redox-dependent viability in lung microvascular endothelial cells.
Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):287-300. doi: 10.1089/ars.2005.7.287.
8
Effect of High-dose Vitamin C Combined With Anti-cancer Treatment on Breast Cancer Cells.
Anticancer Res. 2019 Feb;39(2):751-758. doi: 10.21873/anticanres.13172.

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Targeting ferroptosis: a novel insight into thyroid cancer therapy.
Front Endocrinol (Lausanne). 2025 Jun 3;16:1527693. doi: 10.3389/fendo.2025.1527693. eCollection 2025.
2
Sphingomyelin Metabolism Modifies Luminal A Breast Cancer Cell Line under a High Dose of Vitamin C.
Int J Mol Sci. 2023 Dec 8;24(24):17263. doi: 10.3390/ijms242417263.
3
Integrative Hematology: State of the Art.
Int J Mol Sci. 2023 Jan 15;24(2):1732. doi: 10.3390/ijms24021732.
4
The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia.
Front Cell Dev Biol. 2022 Jul 22;10:930205. doi: 10.3389/fcell.2022.930205. eCollection 2022.
6
Vitamins as Possible Cancer Biomarkers: Significance and Limitations.
Nutrients. 2021 Nov 1;13(11):3914. doi: 10.3390/nu13113914.
7
Kombucha tea from seagrapes () potential as a functional anti-ageing food: and study.
Heliyon. 2021 Sep 8;7(9):e07944. doi: 10.1016/j.heliyon.2021.e07944. eCollection 2021 Sep.
10
Impact of Intravenous Vitamin C and Endolaser Therapies on a Pediatric Brainstem Glioma Case.
Glob Adv Health Med. 2020 Jan 15;9:2164956120901489. doi: 10.1177/2164956120901489. eCollection 2020.

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1
Ascorbic acid alleviates toxicity of paclitaxel without interfering with the anticancer efficacy in mice.
Nutr Res. 2012 Nov;32(11):873-83. doi: 10.1016/j.nutres.2012.09.011. Epub 2012 Oct 26.
3
7
Anti-angiogenic effect of high doses of ascorbic acid.
J Transl Med. 2008 Sep 12;6:50. doi: 10.1186/1479-5876-6-50.
8
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice.
Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. doi: 10.1073/pnas.0804226105. Epub 2008 Aug 4.
9
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.
Proc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. doi: 10.1073/pnas.0702854104. Epub 2007 May 14.
10
Inhibition of corneal angiogenesis by ascorbic acid in the rat model.
Graefes Arch Clin Exp Ophthalmol. 2007 Oct;245(10):1461-7. doi: 10.1007/s00417-007-0542-4. Epub 2007 Feb 21.

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