From the Departments of Radiology and Biomedical Imaging, Division of Women's Imaging (E.R.P., E.A.S., B.N.J.), and Radiology (R.J.B.), University of California, San Francisco, San Francisco, Calif; Department of Radiology (J.H, K.K.L.) and the Comprehensive Cancer Center (D.D.W.), University of California, Davis, Sacramento, Calif; Department of Radiology, Stanford University School of Medicine, Advanced Medicine Center, 875 Blake Wilbur Dr, Room CC-2239, Stanford, Calif (J.A.L., D.M.I.); Bay Imaging Consultants, Sutter Health, Alta Bates Summitt Medical Center, Carol Ann Read Breast Health Center, Oakland, Calif (R.J.B.); Department of Radiology, Sutter Health, California Pacific Medical Center, San Francisco, Calif (J.W.T.L.); Department of Radiology, University of California, Irvine Medical Center, Fong and Jean Tsai Professor of Women's Imaging, University of California Irvine School of Medicine, UCI Medical Center, Orange, Calif (S.A.F.); Department of Radiology, University of California, Los Angeles, Los Angeles, Calif (L.W.B.); Department of Clinical Radiology, Moores Cancer Center, UC San Diego Health System, La Jolla, Calif (H.O.F.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (B.L.D.); Divisions of Oncology and Epidemiology, Stanford University School of Medicine, Stanford, Calif (A.W.K.); Department of OB/GYN, UC Davis Health System, University of California Davis Cancer Center, Sacramento, Calif (E.L.); and Athena Breast Health Network and UCSF Cancer Risk Program, San Francisco, Calif (L.R.).
Radiology. 2013 Dec;269(3):887-92. doi: 10.1148/radiol.13131217. Epub 2013 Oct 28.
In anticipation of breast density notification legislation in the state of California, which would require notification of women with heterogeneously and extremely dense breast tissue, a working group of breast imagers and breast cancer risk specialists was formed to provide a common response framework. The California Breast Density Information Group identified key elements and implications of the law, researching scientific evidence needed to develop a robust response. In particular, issues of risk associated with dense breast tissue, masking of cancers by dense tissue on mammograms, and the efficacy, benefits, and harms of supplementary screening tests were studied and consensus reached. National guidelines and peer-reviewed published literature were used to recommend that women with dense breast tissue at screening mammography follow supplemental screening guidelines based on breast cancer risk assessment. The goal of developing educational materials for referring clinicians and patients was reached with the construction of an easily accessible Web site that contains information about breast density, breast cancer risk assessment, and supplementary imaging. This multi-institutional, multidisciplinary approach may be useful for organizations to frame responses as similar legislation is passed across the United States. Online supplemental material is available for this article.
为应对加利福尼亚州即将出台的乳房密度通知法规（该法规将要求对具有异质和极度致密乳腺组织的女性进行通知），一个由乳腺成像专家和乳腺癌风险专家组成的工作组成立，以提供一个通用的回应框架。加利福尼亚州乳腺密度信息小组确定了该法律的关键要素和影响，研究了制定有力回应所需的科学证据。特别是，对致密乳腺组织相关的风险、乳腺组织在乳房 X 光片中对癌症的掩盖以及补充筛查测试的效果、益处和危害进行了研究并达成共识。国家指南和经过同行评审的已发表文献被用来建议在筛查性乳房 X 光检查中发现致密乳腺组织的女性根据乳腺癌风险评估遵循补充筛查指南。通过构建一个易于访问的网站，包含有关乳腺密度、乳腺癌风险评估和补充成像的信息，实现了为转介临床医生和患者编写教育材料的目标。这种多机构、多学科的方法可能对组织在全美类似立法通过时制定回应措施有用。本文提供了在线补充材料。
