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酒精和烟草滥用:降低气消化道癌症风险。

Alcohol and tobacco misuse: Reducing aerodigestive cancer risk.

作者信息

Wright Gavin, Morgan Marsha Y

机构信息

Gavin Wright, Marsha Y Morgan, UCL Institute for Liver and Digestive Health, Royal Free Campus, University College London Medical School, University College, London NW3 2PF, United Kingdom.

出版信息

World J Hepatol. 2013 Aug 27;5(8):452-7. doi: 10.4254/wjh.v5.i8.452.

Abstract

Significant concerns over the health, social and economic burdens of the two most common, and frequently co-misused drugs of abuse, alcohol and tobacco, has encouraged focused but separate health promotion and disease prevention policies. However, this separation of focus means that while individuals who present with alcohol-related problems are increasingly supported to attain and maintain abstinence from alcohol they are not routinely assisted to refrain from smoking. This is tragically inopportune as alcohol and tobacco have an established "synergistic" effect on aerodigestive cancer risk. Moreover, even when patients successfully tackle their alcohol problems they remain at increased risk for developing these cancers, especially if they continue to smoke. A case series is presented together with a discussion on how service provision for co-misuse could be improved to obviate aerodigestive cancer risk. Given the prevalence of alcohol and tobacco use in the United Kingdom, these observations may have far reaching implications for the individual, health provider(s) and wider society.

摘要

对两种最常见且经常被共同滥用的成瘾药物——酒精和烟草所带来的健康、社会和经济负担的重大担忧,促使人们制定了重点明确但相互独立的健康促进和疾病预防政策。然而,这种关注点的分离意味着,虽然越来越多有酒精相关问题的人得到支持以实现并保持戒酒,但他们却没有经常得到帮助来戒烟。这在悲剧性地不合时宜,因为酒精和烟草对气消化道癌症风险具有既定的“协同”作用。此外,即使患者成功解决了他们的酒精问题,他们患这些癌症的风险仍然会增加,尤其是如果他们继续吸烟的话。本文呈现了一个病例系列,并讨论了如何改进对共同滥用情况的服务提供,以消除气消化道癌症风险。鉴于酒精和烟草在英国的使用 prevalence,这些观察结果可能对个人、医疗服务提供者和更广泛的社会产生深远影响。

原文中“prevalence”可能有误,推测应为“prevalence”,意为“流行程度”“患病率”等,若按此翻译,译文“鉴于酒精和烟草在英国的使用流行程度”会更通顺些。

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2. Tobacco-attributable cancer burden in the UK in 2010.2. 2010年英国烟草所致癌症负担。
Br J Cancer. 2011 Dec 6;105 Suppl 2(Suppl 2):S6-S13. doi: 10.1038/bjc.2011.475.
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3. Cancers attributable to consumption of alcohol in the UK in 2010.3. 2010年英国因饮酒导致的癌症。
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