Badary Amr, Alrefaie Khadeja, Azab Mohammed A, Almealay Yasser F, Alibraheemi Mohammed Q, Awuah Wireko Andrew, Hernández-Hernández Alan, Alrubaye Sura N, Ansari Nabiha Midhat, Tanrikulu Levent, Atallah Oday
Department of Neurosurgery, SRH Wald-Klinikum Gera, Academic Hospital of Jena University, Gera, Germany.
Faculty of Medicine, Royal College of Surgeons in Ireland, Busaiteen, Bahrain.
Neurosurg Rev. 2025 Apr 3;48(1):348. doi: 10.1007/s10143-025-03500-6.
Pericallosal artery aneurysms (PCAA) are relatively rare intracranial aneurysms that present unique challenges in diagnosis and management. This study provides a comprehensive review of the literature to assess demographic patterns, risk factors, treatment approaches, and complications associated with PCAA. Data from 23 studies were analyzed using Python with libraries such as Pandas and Matplotlib. Descriptive statistics and crosstabulations explored the relationships between treatment modalities (microsurgical, endovascular, combined) and complications, including hydrocephalus, vasospasms, and intraprocedural ruptures. Visualizations were employed to depict the prevalence and impact of various outcomes. Analysis revealed a notable gender disparity, with females constituting 70.47% of the study population. The average age was 49.93 years, and the average aneurysm size was 6.34 mm. A majority of aneurysms were ruptured (542 ruptured vs. 251 unruptured). Risk factors like smoking were prevalent, and radiological features such as subarachnoid hemorrhage (SAH) were commonly reported. Endovascular treatment was slightly more frequent (86.96%) than microsurgical treatment (73.91%). Vasospasm was the most reported complication (56.5%), followed by hydrocephalus and intraprocedural rupture. The analysis of the distribution of studies reporting complication for each treatment modality showed that endovascular treatment studies reported higher rates of vasospasms, hydrocephalus and intraprocedural rupture. The mortality rate was 6.52%, with a mean follow-up duration of 20.77 months. This review reveals that PCAAs predominantly affect females, with an average patient age of 49.93 years. Aneurysms averaged 6.34 mm and often caused SAH. Endovascular treatments were more common but had higher complication rates than microsurgical methods, which also carried risks. The mortality rate was 6.52%.
胼周动脉瘤（PCAA）是相对罕见的颅内动脉瘤，在诊断和治疗方面存在独特挑战。本研究对文献进行了全面综述，以评估与PCAA相关的人口统计学模式、危险因素、治疗方法及并发症。使用Python及Pandas和Matplotlib等库对来自23项研究的数据进行了分析。描述性统计和交叉表分析探讨了治疗方式（显微手术、血管内治疗、联合治疗）与并发症之间的关系，这些并发症包括脑积水、血管痉挛和术中破裂。采用可视化方法描绘各种结果的发生率和影响。分析显示存在显著的性别差异，女性占研究人群的70.47%。平均年龄为49.93岁，平均动脉瘤大小为6.34毫米。大多数动脉瘤为破裂型（542例破裂 vs. 251例未破裂）。吸烟等危险因素普遍存在，蛛网膜下腔出血（SAH）等放射学特征也较为常见。血管内治疗的频率略高于显微手术治疗（86.96% 对73.91%）。血管痉挛是报告最多的并发症（56.5%），其次是脑积水和术中破裂。对每种治疗方式报告并发症的研究分布分析表明，血管内治疗研究报告的血管痉挛、脑积水和术中破裂发生率更高。死亡率为6.52%，平均随访时间为20.77个月。本综述表明，PCAA主要影响女性，患者平均年龄为49.93岁。动脉瘤平均大小为6.34毫米，常导致SAH。血管内治疗更为常见，但并发症发生率高于显微手术方法，显微手术方法也有风险。死亡率为6.52%。
