Margo C E, Pautler S E
Department of Ophthalmology, University of Florida, Gainesville.
Retina. 1990;10(2):140-3. doi: 10.1097/00006982-199004000-00010.
Histologic examination of an eye removed 2 years after receiving proton-beam irradiation for a choroidal melanoma revealed residual tumor in the choroid and nonnecrotizing granulomatous inflammation, consistent with the diagnosis of early sympathetic ophthalmia. Sutures that secured four tantulum rings to the sclera did not penetrate the uvea. Sympathetic ophthalmia without evidence of a perforating injury has been described previously after helium ion therapy. The findings in our case further support the hypothesis that there is a risk of developing sympathetic ophthalmia after charged-particle therapy in the absence of a penetrating injury of the uveal tract.
对一例因脉络膜黑色素瘤接受质子束照射两年后摘除的眼球进行组织学检查，发现脉络膜有残留肿瘤以及非坏死性肉芽肿性炎症，符合早期交感性眼炎的诊断。将四个钽环固定于巩膜的缝线未穿透葡萄膜。先前曾有报道称，氦离子治疗后可发生无穿孔伤证据的交感性眼炎。我们病例的发现进一步支持了以下假说：在没有葡萄膜穿透伤的情况下，带电粒子治疗后存在发生交感性眼炎的风险。
