Wammen S, Guldager H, Rasmussen A M, Højsted J
Hvidovre Hospital, Anaestesiologisk afdeling, København.
Ugeskr Laeger. 1990 Aug 20;152(34):2415-7.
Forty patients admitted for elective hemilaminectomy were randomly allocated in two groups: Group I: intravenous anaesthesia with propofol-fentanyl and Group II: Propofol-fentanyl anaesthesia with a supplement of nitrous oxide. The purpose of the study was to investigate whether this supplement involved any advantages or disadvantages for the patients. Mean arterial pressures, awakening times, complications immediately postoperatively and total doses of fentanyl showed no statistically significant differences. In group I (-N2O), the median dose of supplementation with fentanyl was significantly greater, 0.89 micrograms/kg versus 0 in group II (p less than 0.05). We conclude that total intravenous anaesthesia is preferable, because pollution of the air in the operating theatre is avoided.
40例择期行半椎板切除术的患者被随机分为两组：第一组：丙泊酚-芬太尼静脉麻醉；第二组：丙泊酚-芬太尼麻醉并补充氧化亚氮。本研究的目的是调查这种补充对患者是否有任何利弊。平均动脉压、苏醒时间、术后即刻并发症及芬太尼总剂量均无统计学显著差异。在第一组（无氧化亚氮组）中，芬太尼补充的中位剂量显著更高，为0.89微克/千克，而第二组为0（p<0.05）。我们得出结论，全静脉麻醉更可取，因为可避免手术室空气污染。
