Karlsten R, Kristensen J D
Department of Anaesthesiology, University Hospital, Uppsala, Sweden.
Eur J Anaesthesiol. 1993 May;10(3):215-7.
The present study was initiated to evaluate the effects of nitrous oxide on the surgeon's ratings of operating conditions in lower abdominal surgery. Forty patients without known gastrointestinal disorder, scheduled for elective hysterectomy were randomized into one of two groups. In both groups anaesthesia was induced with propofol and endotracheal intubation was performed after administration of vecuronium 0.1 mg kg-1 and anaesthesia was maintained by a propofol infusion. One of the groups was ventilated with O2/air while the other group received nitrous oxide (70%) instead of air. The surgeons were asked to score the operating conditions at the beginning of surgery, when the abdomen was opened, and at the end of the operation, when the peritoneum was to be closed. No difference in rating of operating conditions was found between the two groups. We conclude that the administration of 70% nitrous oxide to patients undergoing lower abdominal surgery does not influence the surgeons ratings of operating conditions.
本研究旨在评估一氧化二氮对下腹部手术中外科医生对手术条件评分的影响。40例计划进行择期子宫切除术且无已知胃肠道疾病的患者被随机分为两组。两组均用丙泊酚诱导麻醉，给予0.1mg/kg维库溴铵后行气管插管，麻醉维持采用丙泊酚输注。其中一组用氧气/空气通气，另一组则用一氧化二氮（70%）替代空气。要求外科医生在手术开始时、打开腹腔时以及手术结束时（即将缝合腹膜时）对手术条件进行评分。两组在手术条件评分上未发现差异。我们得出结论，向下腹部手术患者给予70%的一氧化二氮不会影响外科医生对手术条件的评分。
