Leroux J, Vivier P-H, Grall M, Foulongne E, Ould Slimane M, Abu Amara S, Lechevallier J
Clinique chirurgicale infantile, université de Rouen, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
Arch Pediatr. 2013 Oct;20(10):1139-42. doi: 10.1016/j.arcped.2013.07.005. Epub 2013 Sep 9.
Lyme disease incidence is diverse in France. It is rare in many regions but very frequent in Central and Eastern France. Arthritis is a late manifestation of Lyme disease. In children, the clinical and biological picture often resembles that of septic arthritis and juvenile rheumatoid arthritis, which are more frequent. This explains why diagnosis may be delayed, especially when patient lives in a region of low incidence. We report the case of an 8-year old girl with knee arthritis treated as septic arthritis in a region where Lyme disease is rare. Six days later, clinical and biological worsening suggested that the diagnosis had to be reconsidered. Lyme arthritis was confirmed by serology. Treatment was adapted and the progression was positive. This case reminds us that, in children, Lyme arthritis may look alike septic arthritis or juvenile rheumatoid arthritis and must be considered as a possible diagnosis, even in low-incidence areas.
莱姆病在法国的发病率各不相同。在许多地区较为罕见,但在法国中部和东部地区却非常常见。关节炎是莱姆病的晚期表现。在儿童中,临床和生物学表现通常与更常见的化脓性关节炎和青少年类风湿关节炎相似。这就解释了为什么诊断可能会延迟,尤其是当患者生活在发病率较低的地区时。我们报告了一名8岁患膝关节炎的女孩的病例,在莱姆病罕见的地区,她最初被当作化脓性关节炎治疗。六天后,临床和生物学症状恶化表明必须重新考虑诊断。血清学检查确诊为莱姆关节炎。调整治疗后病情好转。这个病例提醒我们,在儿童中,莱姆关节炎可能与化脓性关节炎或青少年类风湿关节炎相似,即使在发病率低的地区也必须将其视为一种可能的诊断。