Ventura E, Summa A, Ormitti F, Picetti E, Crisi G
Department of Neuroradiology, Parma University Hospital; Parma, Italy -
Neuroradiol J. 2012 Sep;25(4):397-401. doi: 10.1177/197140091202500401. Epub 2012 Sep 6.
In 2009 a novel swine-origin Influenza A H1N1 virus was identified in Mexico and Southern California. Since it was first recognized, neurological complications including acute necrotizing encephalopathy (ANE) have been globally documented in association with this viral infection. ANE is mostly known to occur in the paediatric population. We describe a fatal case of ANE in a previously healthy 40-year-old man infected with influenza A H1N1 virus presenting with severe neurologic decline. Computed tomography (CT) scan and magnetic resonance imaging (MRI) findings were consistent with ANE. CT and MR findings typically documented in paediatric cases of ANE - including bilateral thalamic necrosis with petechial hemorrhage - have been seldom described in adulthood.
2009年，一种新型猪源甲型H1N1流感病毒在墨西哥和南加利福尼亚被发现。自首次被确认以来，包括急性坏死性脑病（ANE）在内的神经系统并发症已在全球范围内被记录与这种病毒感染相关。ANE大多发生在儿科人群中。我们描述了一例先前健康的40岁男性感染甲型H1N1流感病毒后出现严重神经功能衰退的ANE致死病例。计算机断层扫描（CT）和磁共振成像（MRI）结果与ANE相符。ANE儿科病例中典型记录的CT和MR表现——包括双侧丘脑坏死伴瘀点出血——在成人中很少被描述。
