Piñeros Juan Gabriel, Baquero Hernando, Bastidas Jaime, García Jorge, Ovalle Oscar, Patiño Carlos M, Restrepo Juan C
Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia.
J Pediatr (Rio J). 2013 Nov-Dec;89(6):544-8. doi: 10.1016/j.jped.2013.04.002. Epub 2013 Sep 9.
to determine the frequency, complications and seasonality at which respiratory syncytial virus (RSV) infection of the lower respiratory tract causes hospitalization in infants of age 1 year or less in 6 cities of Colombia.
one-year prospective multicentric observational study that included 717 patients presenting to the emergency department with respiratory symptoms in 6 cities of Colombia. Hospitalized children were tested for RSV with an immunofluorescence rapid test in nasopharyngeal secretions. Descriptive and statistical analyses of the population were conducted.
the study population included 717 patients with a mean age of 3.6 months (SD 3.25), 4:3 male: female ratio and a positive RSV LRTI prevalence of 30.0% (216 infants/City, range 26.0 - 49.0%). Risk factors for RSV LRTI were found in 8.2% of the population, of which 28.8% were RSV positive. RSV positive and negative groups were compared using a two-tailed t test with 95.0%CI, p < 0.05. No statistically significant differences were found. All cities presented specific year trimesters in the occurrence of RSV LRTI.
the RSV caused 1 in 3 LRTI hospitalizations in the population, with an incidence of 30.0%. This confirms a continuous circulation of RSV in Colombia varying by geographic location.
确定哥伦比亚6个城市1岁及以下婴儿下呼吸道呼吸道合胞病毒（RSV）感染导致住院的频率、并发症及季节性。
一项为期一年的前瞻性多中心观察性研究，纳入了哥伦比亚6个城市717例因呼吸道症状前往急诊科就诊的患者。对住院儿童的鼻咽分泌物进行免疫荧光快速检测以确定是否感染RSV。对研究人群进行描述性和统计分析。
研究人群包括717例患者，平均年龄3.6个月（标准差3.25），男女比例为4:3，RSV下呼吸道感染（LRTI）的阳性患病率为30.0%（每个城市216例婴儿，范围为26.0 - 49.0%）。8.2%的人群存在RSV LRTI的危险因素，其中28.8%为RSV阳性。使用95.0%置信区间的双尾t检验对RSV阳性和阴性组进行比较，p < 0.05。未发现统计学上的显著差异。所有城市在RSV LRTI的发生上都有特定的年份季度。
RSV导致该人群中三分之一的下呼吸道感染住院，发病率为30.0%。这证实了RSV在哥伦比亚持续传播，且因地理位置而异。
