Facultad de Ciencias Basicas, Universidad Antonio Nariño, Bucaramanga, Colombia.
Fundación Infant, Buenos Aires, Argentina.
BMC Public Health. 2020 Nov 10;20(1):1679. doi: 10.1186/s12889-020-09796-x.
Respiratory syncytial virus infection is the leading cause of bronchiolitis in Colombia. There is growing evidence about the impact of Respiratory syncytial virus on society in terms of years of life lost due to this condition. The objective of the present study is to determine the Disability-Adjusted Life Years for respiratory syncytial virus in children under 2 years in Colombia.
Data from the national epidemiological surveillance system were used to estimate DALYs, calculated from the sum of years of life lost and years lived with disability due to RSV infection in Colombia. A bootstrapped method with 10,000 iterations was used to estimate each statistical parameter using the package DALY calculator in R.
In 2019, 260,873 years of life (CI95% 208,180-347,023) were lost due to RSV bronchiolitis in Colombian children under 2 years. The estimated rate was 20 DALYs / 1000 person-year (95% CI 16-27).
This is the first report estimating the impact of RSV bronchiolitis morbidity and mortality in Colombia. The findings of the present study suggest that the actual burden and cost of bronchiolitis due to RSV is high. Prevention strategies, such as RSV vaccination, to reduce morbidity associated with RSV infection should be encouraged in our country.
呼吸道合胞病毒感染是导致哥伦比亚毛细支气管炎的主要原因。越来越多的证据表明，呼吸道合胞病毒对社会的影响体现在因该疾病而丧失的生命年数上。本研究的目的是确定哥伦比亚 2 岁以下儿童因呼吸道合胞病毒导致的伤残调整生命年。
使用国家流行病学监测系统的数据来估计 DALYs，该数据是通过计算哥伦比亚因 RSV 感染导致的生命年损失和残疾生存年数之和而得出的。使用 R 中的 DALY 计算器包，采用 10,000 次迭代的自举法来估计每个统计参数。
2019 年，哥伦比亚 2 岁以下儿童因 RSV 毛细支气管炎而丧失 260,873 生命年（95%CI95% 208,180-347,023）。估计的发生率为 20 DALYs/1000 人年（95%CI16-27）。
这是首次报告估计 RSV 毛细支气管炎在哥伦比亚的发病率和死亡率的影响。本研究的结果表明，RSV 引起的毛细支气管炎的实际负担和成本很高。应在我国鼓励预防策略，如 RSV 疫苗接种，以减少与 RSV 感染相关的发病率。
