Restrepo Blanca I, Pino Paula A, Zarate Izelda, Mora-Guzman Francisco
Division of Epidemiology, School of Public Health in Brownsville, University of Texas Health Science Center at Houston, 80 Fort Brown, SPH Building, Brownsville, TX 78520, USA.
Int Health. 2013 Jun;5(2):157-9. doi: 10.1093/inthealth/iht007.
Diabetes knowledge among TB patients can contribute to improved TB treatment outcomes, but lack of diabetes diagnosis awareness is a limitation in developing countries. Given its low cost, the sensitivity of urine glucose dipsticks for diabetes screening in TB patients was assessed.
Glycosuria was assessed in 90 newly diagnosed TB patients (38 with diabetes) in south Texas, USA (n = 20) and northeast Mexico (n = 70) during January 2009-December 2010.
Glycosuria was detected in 65% of the diabetic patients with chronic hyperglycemia (positive predictive value 91%, negative predictive value 84%).
We propose that TB clinics with limited budgets where portable glucometers may not be available conduct universal screening for diabetes with urine dipsticks. This could be followed by blood glucose or HbA1c testing in the subset of patients requiring confirmation or higher sensitivity assessment, to improve the comanagement of TB and diabetes.
结核病患者的糖尿病知识有助于改善结核病治疗效果，但在发展中国家，缺乏糖尿病诊断意识是一个限制因素。鉴于尿糖试纸成本低廉，我们评估了其在结核病患者中进行糖尿病筛查的敏感性。
2009年1月至2010年12月期间，对美国得克萨斯州南部（n = 20）和墨西哥东北部（n = 70）的90例新诊断结核病患者（38例患有糖尿病）进行了糖尿评估。
在65%的慢性高血糖糖尿病患者中检测到糖尿（阳性预测值91%，阴性预测值84%）。
我们建议，在预算有限且可能无法使用便携式血糖仪的结核病诊所，使用尿试纸对糖尿病进行普遍筛查。随后可对需要确认或进行更高敏感性评估的患者亚组进行血糖或糖化血红蛋白检测，以改善结核病和糖尿病的联合管理。
