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bla OXA-58 在巴西南部临床样本中分离的鲍曼不动杆菌中的首次出现。

First occurrence of bla OXA-58 in Acinetobacter baumannii isolated from a clinical sample in Southern Brazil.

机构信息

Departamento de Microbiologia, Imunologia e Parasitologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul , Porto Alegre, RS , Brasil.

出版信息

Braz J Microbiol. 2012 Jan;43(1):243-6. doi: 10.1590/S1517-838220120001000027. Epub 2012 Jun 1.

DOI:10.1590/S1517-838220120001000027
PMID:24031824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3768973/
Abstract

This is the first report of an Acinetobacter baumannii from clinical origin carrying the bla OXA-58 gene in Brazil. The isolate included in this study was from a patient during an outbreak in Porto Alegre, RS, Southern Brazil, in 2007. It was resistant to most of the beta-lactams tested, it has also the bla OXA-65 gene and the ISAbal sequence located upstream to both bla OXA genes detected and it has a MIC of imipenem of 64 μg/mL.

摘要

这是巴西首例携带 bla OXA-58 基因的临床来源鲍曼不动杆菌的报告。本研究中分离到的菌株来自 2007 年巴西南部南里奥格兰德州阿雷格里港爆发疫情中的一名患者。它对大多数测试的β-内酰胺类药物均具有耐药性，还携带 bla OXA-65 基因和位于 bla OXA 基因上游的 ISAbal 序列，其亚胺培南 MIC 为 64μg/mL。

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