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A nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58.一次由表达碳青霉烯水解型奥沙西林酶OXA - 58的鲍曼不动杆菌分离株引起的医院感染暴发。
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本文引用的文献

1
High prevalence of carbapenem-hydrolysing oxacillinases in epidemiologically related and unrelated Acinetobacter baumannii clinical isolates in Spain.西班牙流行病学相关及不相关鲍曼不动杆菌临床分离株中碳青霉烯水解型苯唑西林酶的高流行率
Clin Microbiol Infect. 2007 Dec;13(12):1192-8. doi: 10.1111/j.1469-0691.2007.01825.x. Epub 2007 Sep 10.
2
Molecular epidemiology and characterization of resistance mechanisms to various antimicrobial agents in Acinetobacter baumannii isolated in Mérida, Venezuela.委内瑞拉梅里达分离的鲍曼不动杆菌的分子流行病学及对各种抗菌药物耐药机制的特征分析
Med Sci Monit. 2007 Apr;13(4):BR89-94.
3
Porins, efflux pumps and multidrug resistance in Acinetobacter baumannii.鲍曼不动杆菌中的孔蛋白、外排泵与多重耐药性
J Antimicrob Chemother. 2007 Jun;59(6):1210-5. doi: 10.1093/jac/dkl509. Epub 2007 Feb 26.
4
Distinct antimicrobial resistance patterns and antimicrobial resistance-harboring genes according to genomic species of Acinetobacter isolates.根据不动杆菌分离株的基因组种别呈现的不同抗菌药物耐药模式及携带抗菌药物耐药性的基因
J Clin Microbiol. 2007 Mar;45(3):902-5. doi: 10.1128/JCM.01573-06. Epub 2006 Dec 27.
5
Nosocomial spread of OXA-58-positive carbapenem-resistant Acinetobacter baumannii isolates in a paediatric hospital in Greece.希腊一家儿科医院中OXA-58阳性耐碳青霉烯鲍曼不动杆菌菌株的医院内传播。
Clin Microbiol Infect. 2006 Nov;12(11):1138-41. doi: 10.1111/j.1469-0691.2006.01537.x.
6
Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology.鲍曼不动杆菌对碳青霉烯类抗生素的耐药性:机制与流行病学
Clin Microbiol Infect. 2006 Sep;12(9):826-36. doi: 10.1111/j.1469-0691.2006.01456.x.
7
High prevalence of OXA-51-type class D beta-lactamases among ceftazidime-resistant clinical isolates of Acinetobacter spp.: co-existence with OXA-58 in multiple centres.不动杆菌属对头孢他啶耐药临床分离株中OXA-51型D类β-内酰胺酶的高流行率:在多个中心与OXA-58共存
J Antimicrob Chemother. 2006 Sep;58(3):537-42. doi: 10.1093/jac/dkl273. Epub 2006 Jul 1.
8
Genetic structures at the origin of acquisition and expression of the carbapenem-hydrolyzing oxacillinase gene blaOXA-58 in Acinetobacter baumannii.鲍曼不动杆菌中碳青霉烯水解型苯唑西林酶基因blaOXA - 58获得与表达起源处的遗传结构
Antimicrob Agents Chemother. 2006 Apr;50(4):1442-8. doi: 10.1128/AAC.50.4.1442-1448.2006.
9
Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.用于检测不动杆菌属中常见OXA碳青霉烯酶编码基因的多重聚合酶链反应
Int J Antimicrob Agents. 2006 Apr;27(4):351-3. doi: 10.1016/j.ijantimicag.2006.01.004. Epub 2006 Mar 24.
10
Inter-country transfer of Gram-negative organisms carrying the VIM-4 and OXA-58 carbapenem-hydrolysing enzymes.携带VIM-4和OXA-58碳青霉烯水解酶的革兰氏阴性菌的跨国传播。
J Antimicrob Chemother. 2006 Apr;57(4):794-5. doi: 10.1093/jac/dkl036. Epub 2006 Feb 13.

不动杆菌基因种3临床分离株中碳青霉烯水解型苯唑西林酶oxa - 58的特性分析

Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate.

作者信息

Marti Sara, Sánchez-Céspedes Javier, Blasco M Dolores, Ruiz Marc, Espinal Paula, Alba Verónica, Fernández-Cuenca Felipe, Pascual Alvaro, Vila Jordi

机构信息

Servei de Microbiologia, Centre de Diagnóstic Biomèdic, Hospital Clínic, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.

出版信息

Antimicrob Agents Chemother. 2008 Aug;52(8):2955-8. doi: 10.1128/AAC.00072-08. Epub 2008 May 27.

DOI:10.1128/AAC.00072-08
PMID:18505859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2493133/
Abstract

Based on imipenem resistance in an Acinetobacter genospecies 3 clinical isolate, we were able to identify, for the first time in this genomic species, a plasmid-encoded bla(OXA-58) gene that was 100% homologous to the same gene in Acinetobacter baumannii.

摘要

基于不动杆菌基因种3临床分离株对亚胺培南的耐药性,我们首次在该基因组种中鉴定出一个质粒编码的bla(OXA-58)基因,该基因与鲍曼不动杆菌中的相同基因具有100%的同源性。