Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans: Lost in translation.
作者信息
Hysek Cédric M, Schmid Yasmin, Rickli Anna, Liechti Matthias E
机构信息
Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Internal Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
出版信息
Br J Pharmacol. 2013 Nov;170(6):1273-5. doi: 10.1111/bph.12398.
Abstract
摘要
相似文献
1
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans: Lost in translation.卡维地洛可抑制摇头丸对人体的心脏刺激和产热作用：翻译中的遗漏。
Br J Pharmacol. 2013 Nov;170(6):1273-5. doi: 10.1111/bph.12398.
2
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans.卡维地洛可抑制摇头丸对人体的心脏兴奋和产热作用。
Br J Pharmacol. 2013 Nov;170(6):1272. doi: 10.1111/bph.12258.
3
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans.卡维地洛抑制 MDMA 在人体中的心脏刺激和生热作用。
Br J Pharmacol. 2012 Aug;166(8):2277-88. doi: 10.1111/j.1476-5381.2012.01936.x.
4
Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug-drug interactions.3,4-亚甲二氧基甲基苯丙胺（MDMA）的药代动力学和药效学：由于多态性和药物相互作用导致的个体间差异。
Crit Rev Toxicol. 2012 Nov;42(10):854-76. doi: 10.3109/10408444.2012.725029. Epub 2012 Oct 3.
5
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.单独使用 MDMA 以及预先使用瑞波西汀、度洛西汀、可乐定、卡维地洛和多沙唑嗪预处理对瞳孔光反射的影响。
Psychopharmacology (Berl). 2012 Dec;224(3):363-76. doi: 10.1007/s00213-012-2761-6. Epub 2012 Jun 15.
6
Carvedilol affects the physiological and behavioral response to smoked cocaine in humans.卡维地洛影响人类对吸食可卡因的生理和行为反应。
Drug Alcohol Depend. 2000 Jul 1;60(1):69-76. doi: 10.1016/s0376-8716(99)00143-x.
7
COMET: a proposed mechanism of action to explain the results and concerns about dose.COMET：一种用以解释结果及剂量相关问题的拟议作用机制。
Lancet. 2003 Sep 27;362(9389):1077; author reply 1077-8. doi: 10.1016/S0140-6736(03)14422-4.
8
Adrenergic blocker carvedilol attenuates the cardiovascular and aversive effects of nicotine in abstinent smokers.肾上腺素能阻滞剂卡维地洛可减轻戒烟者体内尼古丁的心血管及厌恶效应。
Behav Pharmacol. 2006 Dec;17(8):731-5. doi: 10.1097/FBP.0b013e32801155d4.
9
Clinically Relevant Pharmacological Strategies That Reverse MDMA-Induced Brain Hyperthermia Potentiated by Social Interaction.逆转由社交互动增强的摇头丸诱导的脑部高温的临床相关药理学策略。
Neuropsychopharmacology. 2016 Jan;41(2):549-59. doi: 10.1038/npp.2015.182. Epub 2015 Jun 24.
10
α₁-Adrenergic receptors contribute to the acute effects of 3,4-methylenedioxymethamphetamine in humans.α₁-肾上腺素能受体有助于 3,4-亚甲二氧基甲基苯丙胺对人类的急性作用。
J Clin Psychopharmacol. 2013 Oct;33(5):658-66. doi: 10.1097/JCP.0b013e3182979d32.
引用本文的文献
1
The effect of MDMA on anterior pituitary hormones: a secondary analysis of a randomized placebo-controlled trial.摇头丸对垂体前叶激素的影响：一项随机安慰剂对照试验的二次分析。
Endocr Connect. 2025 Jun 18;14(6). doi: 10.1530/EC-25-0254. Print 2025 Jun 1.
2
Effects of MDMA on body temperature in humans.摇头丸对人体体温的影响。
Temperature (Austin). 2014 Oct 31;1(3):192-200. doi: 10.4161/23328940.2014.955433. eCollection 2014 Oct-Dec.
3
Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia.甲基苯丙胺诱导的毒性：关于与体温过高相关问题的最新综述
Pharmacol Ther. 2014 Oct;144(1):28-40. doi: 10.1016/j.pharmthera.2014.05.001. Epub 2014 May 14.
4
Inhibition of the dorsomedial hypothalamus, but not the medullary raphe pallidus, decreases hyperthermia and mortality from MDMA given in a warm environment.抑制下丘脑背内侧核而非延髓中缝苍白核，可降低在温暖环境中给予摇头丸所致的体温过高和死亡率。
Pharmacol Res Perspect. 2014 Apr 1;2(2):e00031. doi: 10.1002/prp2.31.
本文引用的文献
1
α₁-Adrenergic receptors contribute to the acute effects of 3,4-methylenedioxymethamphetamine in humans.α₁-肾上腺素能受体有助于 3,4-亚甲二氧基甲基苯丙胺对人类的急性作用。
J Clin Psychopharmacol. 2013 Oct;33(5):658-66. doi: 10.1097/JCP.0b013e3182979d32.
2
3,4-Methylenedioxymethamphetamine induces a hyperthermic and hypermetabolic crisis in pigs with and without a genetic disposition for malignant hyperthermia.3,4-亚甲二氧基甲基苯丙胺可引起具有和不具有恶性高热遗传易感性的猪发生高热和高代谢危机。
Eur J Anaesthesiol. 2013 Jan;30(1):29-37. doi: 10.1097/EJA.0b013e32835a1127.
3
A randomized, controlled pilot study of MDMA (± 3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD).一项关于 MDMA（± 3,4-亚甲二氧基甲基苯丙胺）辅助心理治疗治疗耐药性慢性创伤后应激障碍（PTSD）的随机对照初步研究。
J Psychopharmacol. 2013 Jan;27(1):40-52. doi: 10.1177/0269881112464827. Epub 2012 Oct 31.
4
Pharmacokinetics and pharmacodynamics of 3,4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug-drug interactions.3,4-亚甲二氧基甲基苯丙胺（MDMA）的药代动力学和药效学：由于多态性和药物相互作用导致的个体间差异。
Crit Rev Toxicol. 2012 Nov;42(10):854-76. doi: 10.3109/10408444.2012.725029. Epub 2012 Oct 3.
5
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.单独使用 MDMA 以及预先使用瑞波西汀、度洛西汀、可乐定、卡维地洛和多沙唑嗪预处理对瞳孔光反射的影响。
Psychopharmacology (Berl). 2012 Dec;224(3):363-76. doi: 10.1007/s00213-012-2761-6. Epub 2012 Jun 15.
6
Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study.度洛西汀在一项随机安慰剂对照实验室研究中体外和在人体中抑制 MDMA（“摇头丸”）的作用。
PLoS One. 2012;7(5):e36476. doi: 10.1371/journal.pone.0036476. Epub 2012 May 4.
7
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans.卡维地洛抑制 MDMA 在人体中的心脏刺激和生热作用。
Br J Pharmacol. 2012 Aug;166(8):2277-88. doi: 10.1111/j.1476-5381.2012.01936.x.
8
Linking the pharmacological content of ecstasy tablets to the subjective experiences of drug users.将摇头丸的药理学内容与使用者的主观体验联系起来。
Psychopharmacology (Berl). 2012 Apr;220(4):751-62. doi: 10.1007/s00213-011-2529-4. Epub 2011 Oct 13.
9
MDMA and temperature: a review of the thermal effects of 'Ecstasy' in humans.MDMA 和体温：对“摇头丸”在人体内产生的热效应的综述。
Drug Alcohol Depend. 2012 Feb 1;121(1-2):1-9. doi: 10.1016/j.drugalcdep.2011.08.012. Epub 2011 Sep 15.
10
Pill content, dose and resulting plasma concentrations of 3,4-methylendioxymethamphetamine (MDMA) in recreational 'ecstasy' users.娱乐用摇头丸（MDMA）中 3,4-亚甲二氧基甲基苯丙胺（MDMA）的丸芯内容物、剂量和血浆浓度。
Addiction. 2011 Jul;106(7):1293-300. doi: 10.1111/j.1360-0443.2011.03399.x. Epub 2011 May 3.
Zotero 插件