Bueno Alvaro, Rotellar Fernando, Benito Alberto, Martí-Cruchaga Pablo, Zozaya Gabriel, Hermida José, Pardo Fernando
Department of General and Abdominal Surgery, University of Navarra, Pamplona, Spain.
HPB (Oxford). 2014 Apr;16(4):320-6. doi: 10.1111/hpb.12147. Epub 2013 Aug 22.
The laparoscopic approach is widely used in abdominal surgery. However, the benefits of laparoscopy in liver surgery have hitherto been insufficiently established. This study sought to investigate these benefits and, in particular, to establish whether or not the laparoscopic approach is beneficial in patients with lesions involving the posterosuperior segments of the liver.
Outcomes in a cohort of patients undergoing mostly minor hepatectomy (50 laparoscopic and 52 open surgery procedures) between January 2000 and December 2010 at the University Clinic of Navarra were analysed. The two groups displayed similar clinical characteristics.
Patients submitted to laparoscopic liver resection (LLR) had a lower risk for complications [odds ratio (OR) = 0.24, 95% confidence interval (CI) 0.07-0.74; P = 0.013] and shorter hospital stay (OR = 0.08, 95% CI 0.02-0.27; P < 0.001) independently of the presence of classical risk factors for complications. In the cohort of patients with lesions involving posterosuperior liver segments (20 laparoscopic, 21 open procedures), LLR was associated with significantly fewer complications (OR = 0.16, 95% CI 0.04-0.71) and a lower risk for a long hospital stay (OR = 0.1, 95% CI 0.02-0.43).
This study confirms that the laparoscopic approach to hepatic resection decreases the risk for post-surgical complications and lengthy hospitalization in patients undergoing minor liver resections. This beneficial effect is observed even in patients with lesions located in segments that require technically difficult resections.
腹腔镜手术方法在腹部手术中被广泛应用。然而,腹腔镜手术在肝脏手术中的益处迄今尚未得到充分证实。本研究旨在探究这些益处,尤其是确定腹腔镜手术方法对肝脏后上段有病变的患者是否有益。
分析了2000年1月至2010年12月在纳瓦拉大学诊所接受大部分为小肝切除术(50例腹腔镜手术和52例开放手术)的一组患者的结果。两组患者具有相似的临床特征。
接受腹腔镜肝切除术(LLR)的患者发生并发症的风险较低[比值比(OR)=0.24,95%置信区间(CI)0.07 - 0.74;P = 0.013],且住院时间较短(OR = 0.08,95%CI 0.02 - 0.27;P < 0.001),与是否存在并发症的经典危险因素无关。在肝脏后上段有病变的患者队列中(20例腹腔镜手术,21例开放手术),LLR与显著较少的并发症(OR = 0.16,95%CI 0.04 - 0.71)以及较长住院时间的较低风险(OR = 0.1,95%CI 0.02 - 0.43)相关。
本研究证实,腹腔镜肝切除术可降低接受小肝切除术患者的术后并发症风险和延长住院时间。即使在需要进行技术难度较大切除的肝段有病变的患者中也观察到了这种有益效果。